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© Research
Publication : The American journal of tropical medicine and hygiene

Dengue seroprevalence in the French West Indies: a prospective study in adult blood donors

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The American journal of tropical medicine and hygiene - 06 Apr 2015

L'Azou M, Jean-Marie J, Bessaud M, Cabié A, Césaire R, de Lamballerie X, Courbil R, Richard P

Link to Pubmed [PMID] – 25846291

Am. J. Trop. Med. Hyg. 2015 Jun;92(6):1137-40

Using an anti-dengue immunoglobulin G (IgG) indirect enzyme-linked immunosorbent assay, seroprevalence was determined among 783 adult blood donors in the French Caribbean islands of Guadeloupe and Martinique in 2011. Overall, 93.5% [91.5; 95.1] samples were positive for dengue antibodies, 90.7% (350 of 386) in Martinique and 96.2% (382 of 397) in Guadeloupe. Only 30% of these adults recalled having had dengue disease before. Serotype-specific neutralization assays applied to a subset of IgG-positive samples indicated that a majority (77 of 96; 80%) reacted to the four serotypes. These seroprevalence findings are the first reported for Guadeloupe and Martinique and are consistent with the dengue epidemiology in these territories.

http://www.ncbi.nlm.nih.gov/pubmed/25846291