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© Research
Publication : BMC neuroscience

Defined α-synuclein prion-like molecular assemblies spreading in cell culture

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in BMC neuroscience - 04 Jun 2014

Aulić S, Le TT, Moda F, Abounit S, Corvaglia S, Casalis L, Gustincich S, Zurzolo C, Tagliavini F, Legname G

Link to Pubmed [PMID] – 24898419

BMC Neurosci 2014;15:69

α-Synuclein (α-syn) plays a central role in the pathogenesis of synucleinopathies, a group of neurodegenerative disorders that includes Parkinson disease, dementia with Lewy bodies and multiple system atrophy. Several findings from cell culture and mouse experiments suggest intercellular α-syn transfer.

http://www.ncbi.nlm.nih.gov/pubmed/24898419