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© Research
Publication : Bioinformatics (Oxford, England)

Data mining techniques to study the disulfide-bonding state in proteins: signal peptide is a strong descriptor

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Bioinformatics (Oxford, England) - 27 May 2004

Tessier D, Bardiaux B, Larré C, Popineau Y

Link to Pubmed [PMID] – 15166026

Bioinformatics 2004 Nov;20(16):2509-12

In the eucaryotic cell, the formation of disulfide bonds takes place in general inside the endoplasmic reticulum which provides a unique folding environment. The DisulfideDB database gathers information about this biological process with structural, evolutionary and neighborhood information on cysteines in proteins. Mining this information with an association rule discovery program permits to extract some strong rules for the prediction of the disulfide-bonding state of cysteines.

http://www.ncbi.nlm.nih.gov/pubmed/15166026