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© Research
Publication : Trends in microbiology

CRISPR-Cas and restriction-modification team up to achieve long-term immunity.

Team: Molecular diversity of microbes
Member: Aude Bernheim
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Trends in microbiology - 01 Jun 2022

Cury J, Bernheim A

Link to Pubmed [PMID] – 35469710

Link to DOI – 10.1016/j.tim.2022.04.001

Trends Microbiol 2022 Jun; 30(6): 513-514

Bacteria have been shown to harbor a growing arsenal of various defense systems against phages. Maguin et al. have uncovered how two of the most frequent defense systems interact: the clustered regularly interspaced short palindromic repeats-Cas (CRISPR-Cas) system recycles by-products of the restriction-modification (RM) system to increase bacterial defense in the long run.