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© Research
Publication : Nature cell biology

Connecting membrane traffic to ESCRT and the final cut

Team: Membrane Traffic and Cell Division
Member: Arnaud Echard
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Nature cell biology - 01 Oct 2012

Echard A

Link to Pubmed [PMID] – 23033048

Nat. Cell Biol. 2012 Oct;14(10):983-5

The ESCRT (endosomal sorting complex required for transport) machinery is responsible for scission of the cytokinetic bridge that connects daughter cells at the end of mitosis. Specific endosomes are now found to mediate local bridge constriction and actin clearance in human cells, which contribute to the recruitment of ESCRT components at the abscission site.