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© Research
Publication : Antimicrobial agents and chemotherapy

Colonization of extended-spectrum-β-lactamase- and NDM-1-producing Enterobacteriaceae among pregnant women in the community in a low-income country: a potential reservoir for transmission of multiresistant Enterobacteriaceae to neonates

Team: Epidemiology and Modelling of Antibacterial Evasion (EMAE)
Member: Didier Guillemot
Member: Bich-Tram Huynh
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Antimicrobial agents and chemotherapy - 06 Apr 2015

Chereau F, Herindrainy P, Garin B, Huynh BT, Randrianirina F, Padget M, Piola P, Guillemot D, Delarocque-Astagneau E

Link to Pubmed [PMID] – 25845871

Antimicrob. Agents Chemother. 2015;59(6):3652-5

The spread of extended-spectrum-β-lactamase-producing Enterobacteriaceae (ESBL-PE) in low-income countries, where the burden of neonatal sepsis is high, may have a serious impact on neonatal mortality rates. Given the potential for mother-to-child transmission of multiresistant bacteria, this study investigated the ESBL-PE rectal colonization among pregnant women at delivery in the community in Madagascar and estimated a prevalence of 18.5% (95% confidence interval, 14.5% to 22.6%). One strain of Klebsiella pneumoniae isolated was also a New Delhi metallo-β-lactamase-1 (NDM-1) producer.