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© Christine Schmitt, Anubis Vega Rua, Jean-Marc Panaud
Tête de moustique femelle Aedes albopictus, vecteur du virus de la dengue et du chikungunya. Microphotographie électronique à balayage, image colorisée.
Publication : Viruses

Chikungunya Virus Replication in Salivary Glands of the Mosquito Aedes albopictus

Team: Arboviruses and Insect Vectors
Team: Ultrastructural BioImaging
Member: Marie Vazeille
Member: Christine Schmitt
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Viruses - 17 Nov 2015

Vega-Rúa A, Schmitt C, Bonne I, Krijnse Locker J, Failloux AB

Link to Pubmed [PMID] – 26593936

Viruses 2015 Nov;7(11):5902-7

Chikungunya virus (CHIKV) is an emerging arbovirus transmitted to humans by mosquitoes such as Aedes albopictus. To be transmitted, CHIKV must replicate in the mosquito midgut, then disseminate in the hemocele and infect the salivary glands before being released in saliva. We have developed a standardized protocol to visualize viral particles in the mosquito salivary glands using transmission electron microscopy. Here we provide direct evidence for CHIKV replication and storage in Ae. albopictus salivary glands.