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© Research
Publication : Foodborne pathogens and disease

Characterization of Listeria monocytogenes strains isolated during 2011-2013 from human infections in Switzerland

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Foodborne pathogens and disease - 09 Jul 2014

Althaus D, Lehner A, Brisse S, Maury M, Tasara T, Stephan R

Link to Pubmed [PMID] – 25007293

Foodborne Pathog. Dis. 2014 Oct;11(10):753-8

Listeria monocytogenes, an emerging foodborne pathogen, can cause in the population at risk severe infections that are associated with high case fatality rates. A total of 93 L. monocytogenes strains isolated from different patients in Switzerland from July 2011 to September 2013 were further characterized. Septicemia was reported for 74.2% of the patients, meningitis for 10.8%, and abortion for 3.2%. The majority of the strains belonged to serotype 1/2a (n=58) followed by serotype 4b (n=28), 1/2b (n=5), and 1/2c (n=2). The strains represented 35 multilocus sequence typing sequence types, 8 of which were designated for the first time. Sequence analysis of the inlA gene in the 35 sequence types showed that most of the strains encoded full-length proteins. Screening for Listeriolysin S showed the presence of this virulence factor in 29 of the 33 genetic lineage I strains. By using ApaI and AscI for pulsed-field gel electrophoresis, most strains showed distinguishable patterns.

http://www.ncbi.nlm.nih.gov/pubmed/25007293