Link to Pubmed [PMID] – 15271951
Infect. Immun. 2004 Aug;72(8):4874-7
We describe a clinical isolate of Bordetella pertussis, the agent responsible for whooping cough, composed of at least two clones harboring one or two copies of the cya locus encoding one of the major toxins, adenylate cyclase-hemolysin. No difference was observed between the two clones in murine and cellular models, probably due to the high instability of the cya locus duplication.