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© Research
Publication : Antimicrobial agents and chemotherapy

Characterization of a Carbapenem-Resistant BKC-1-Producing Clinical Isolate Belonging to the Pseudomonas putida Group from Brazil.

Member: Carolina Nodari
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Antimicrobial agents and chemotherapy - 15 Nov 2022

Alberto-Lei F, Nodari CS, Streling AP, Bessa-Neto FO, Siqueira AV, Cayô R, Gales AC,

Link to Pubmed [PMID] – 36377877

Link to DOI – 10.1128/aac.00839-22

Antimicrob Agents Chemother 2022 Nov; (): e0083922

Since its first report, the class A Brazilian Klebsiella carbapenemase (BKC) has been detected only among Enterobacterales isolates from Brazilian hospitals. In this study, we characterized a multidrug-resistant Pseudomonas juntendi clinical isolate and identified a 43.3-kb plasmid carrying blaBKC-1 and a class 1 integron (In1996) containing the arr-2, qnrVC1, dfrA21, and aac(6′)-Ib’ gene cassettes. Our results confirm the ability of Pseudomonas putida group isolates to acquire antimicrobial resistance determinants and further act as resistance reservoirs.