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© Research
Publication : Emerging infectious diseases

Bacterial Infections in Neonates, Madagascar, 2012-2014

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Emerging infectious diseases - 01 Apr 2018

Huynh BT, Kermorvant-Duchemin E, Herindrainy P, Padget M, Rakotoarimanana FMJ, Feno H, Hariniaina-Ratsima E, Raheliarivao T, Ndir A, Goyet S, Piola P, Randrianirina F, Garin B, Collard JM, Guillemot D, Delarocque-Astagneau E

Link to Pubmed [PMID] – 29553312

Emerging Infect. Dis. 2018 04;24(4):710-717

Severe bacterial infections are a leading cause of death among neonates in low-income countries, which harbor several factors leading to emergence and spread of multidrug-resistant bacteria. Low-income countries should prioritize interventions to decrease neonatal infections; however, data are scarce, specifically from the community. To assess incidence, etiologies, and antimicrobial drug-resistance patterns of neonatal infections, during 2012-2014, we conducted a community-based prospective investigation of 981 newborns in rural and urban areas of Madagascar. The incidence of culture-confirmed severe neonatal infections was high: 17.7 cases/1,000 live births. Most (75%) occurred during the first week of life. The most common (81%) bacteria isolated were gram-negative. The incidence rate for multidrug-resistant neonatal infection was 7.7 cases/1,000 live births. In Madagascar, interventions to improve prevention, early diagnosis, and management of bacterial infections in neonates should be prioritized.

https://www.ncbi.nlm.nih.gov/pubmed/29553312