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© Research
Publication : Tropical medicine and health

Asymptomatic infections among Duffy-negative population in Kedougou, Senegal

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Tropical medicine and health - 29 Dec 2018

Niang M, Sane R, Sow A, Sadio BD, Chy S, Legrand E, Faye O, Diallo M, Sall AA, Menard D, Toure-Balde A

Link to Pubmed [PMID] – 30618490

Trop Med Health 2018;46:45

Background: In the southeastern Senegal, the report of infections among febrile patients in Kedougou constitutes a new emerging health problem.

Methods: Samples from 48 asymptomatic schoolchildren sampled twice a year over 2 years were used to explore the reservoir of parasite infections in this region. Both Duffy genotyping and species diagnostic assays were performed.

Results: PCR assays detected genomic DNA in 38.5% (74/192) of samples. Pure and infections were identified in 79.7% (59/74) and 20.3% (15/74) of samples, respectively. All schoolchildren were classified as Duffy-negative by genotyping. infections were detected in five children: in two children during both years, in one child in 2010 and on May 2011, and only in 2010 for the remaining two children.

Conclusions: This unexpectedly high proportion of infections in asymptomatic Duffy-negative children highlights to consider vivax malaria as an emerging problem in Senegal.

https://www.ncbi.nlm.nih.gov/pubmed/30618490