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© Research
Publication : Clinical infectious diseases : an official publication of the Infectious Diseases Society of America

Association between circulating DNA, serum (1->3)-β-D-glucan, and pulmonary fungal burden in Pneumocystis pneumonia

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America - 20 Apr 2012

Costa JM, Botterel F, Cabaret O, Foulet F, Cordonnier C, Bretagne S

Link to Pubmed [PMID] – 22523258

Clin. Infect. Dis. 2012 Jul;55(2):e5-8

Circulating Pneumocystis jirovecii DNA and (1→3)-β-d-glucan determined in 70 serum samples from immunocompromised patients were compared to fungal load in bronchoalveolar lavage fluids assessed using quantitative polymerase chain reaction. Both serum biomarkers are influenced by pulmonary fungal load, which should be taken into account when diagnosing Pneumocystis infection.