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© Pierre Gounon
Virus influenza purifié, agent de la grippe. Ce virus enveloppé possède un génome fragmenté : 8 segments d'ARN négatif protégés par une nucléocapside.
Publication : PloS one

Application of high-density DNA resequencing microarray for detection and characterization of botulinum neurotoxin-producing clostridia

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in PloS one - 20 Jun 2013

Vanhomwegen J, Berthet N, Mazuet C, Guigon G, Vallaeys T, Stamboliyska R, Dubois P, Kennedy GC, Cole ST, Caro V, Manuguerra JC, Popoff MR

Link to Pubmed [PMID] – 23818983

PLoS ONE 2013;8(6):e67510

Clostridium botulinum and related clostridia express extremely potent toxins known as botulinum neurotoxins (BoNTs) that cause severe, potentially lethal intoxications in humans. These BoNT-producing bacteria are categorized in seven major toxinotypes (A through G) and several subtypes. The high diversity in nucleotide sequence and genetic organization of the gene cluster encoding the BoNT components poses a great challenge for the screening and characterization of BoNT-producing strains.

http://www.ncbi.nlm.nih.gov/pubmed/23818983