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© Research
Publication : eLife

An arbitrary-spectrum spatial visual stimulator for vision research.

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in eLife - 23 Sep 2019

Franke K, Maia Chagas A, Zhao Z, Zimmermann MJ, Bartel P, Qiu Y, Szatko KP, Baden T, Euler T,

Link to Pubmed [PMID] – 31545172

Link to DOI – 10.7554/eLife.48779e48779

Elife 2019 09; 8():

Visual neuroscientists require accurate control of visual stimulation. However, few stimulator solutions simultaneously offer high spatio-temporal resolution and free control over the spectra of the light sources, because they rely on off-the-shelf technology developed for human trichromatic vision. Importantly, consumer displays fail to drive UV-shifted short wavelength-sensitive photoreceptors, which strongly contribute to visual behaviour in many animals, including mice, zebrafish and fruit flies. Moreover, many non-mammalian species feature more than three spectral photoreceptor types. Here, we present a flexible, spatial visual stimulator with up to six arbitrary spectrum chromatic channels. It combines a standard digital light processing engine with open source hard- and software that can be easily adapted to the experimentalist’s needs. We demonstrate the capability of this general visual stimulator experimentally in the in vitro mouse retinal whole-mount and the in vivo zebrafish. With this work, we intend to start a community effort of sharing and developing a common stimulator design for vision research.

https://pubmed.ncbi.nlm.nih.gov/31545172