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© Research
Publication : Diagnostic and interventional imaging

Advanced technologies applied to physiopathological analysis of central nervous system aneurysms and vascular malformations

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Diagnostic and interventional imaging - 03 Jun 2014

Edjlali M, Roca P, Gentric JC, Trystram D, Rodriguez-Régent C, Nataf F, Chrétien F, Wieben O, Turski P, Meder JF, Naggara O, Oppenheim C

Link to Pubmed [PMID] – 24933269

Diagn Interv Imaging 2014 Dec;95(12):1187-93

While depiction and definition of morphological and architectural characteristics of CNS vascular disorders remains the first step of an MR analysis, emerging imaging techniques offer new functional information that might help to characterize rupture risk of CNS vascular disorders. Two main orientations are suggested by recent studies: inflammation of the vessel wall and analysis of physical constraints of blood flow using 4D flow imaging (shear parietal). This paper will focus on radiological application of 4D flow imaging and inflammation imaging, in the characterization of potential prognostic markers of CNS vascular disorders. We will review the basic technical considerations of 4D flow MRA, inflammation imaging and discuss their applications in CNS vascular disorders: aneurysms, arteriovenous malformation, dural arteriovenous fistulas. We will illustrate their potential in the development of individual rupture risk criteria in brain vascular disorders.