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© Research
Publication : Neurosurgery clinics of North America

Adult neurogenesis and hippocampal memory function: new cells, more plasticity, new memories?

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Neurosurgery clinics of North America - 01 Jan 2007

Kitabatake Y, Sailor KA, Ming GL, Song H

Link to Pubmed [PMID] – 17244558

Neurosurg. Clin. N. Am. 2007 Jan;18(1):105-13, x

The discovery of active adult neurogenesis in mammals, a process of generating functional neurons from neural stem cells, suggests that the adult brain is more dynamic than once imagined. The coincidence of this phenomenon occurring in the hippocampus, a region critical to the learning process, begs the question of whether adult neurogenesis is involved in memory formation. Here, the authors review rapidly accumulating evidence showing a strong correlation between certain types of memory functions and adult neurogenesis in the hippocampus. Establishment of the potential link between memory formation and adult neurogenesis is instrumental, at a basic science level, to understand the function of neural networks and is essential, at a clinical level, to develop effective therapies for various cognitive dysfunctions.