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© Research
Publication : The Journal of antimicrobial chemotherapy

Accumulation of CVIET Pfcrt allele of Plasmodium falciparum in placenta of pregnant women living in an urban area of Dakar, Senegal

Team: Biomics
Member: Christiane Bouchier
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in The Journal of antimicrobial chemotherapy - 05 Aug 2008

Niang M, Marrama L, Ekala MT, Alioune G, Tall A, Ndiaye JL, Sarr D, Dangou JM, Lehesran JY, Bouchier C, Mercereau-Puijalon O, Jambou R

Link to Pubmed [PMID] – 18682531

J. Antimicrob. Chemother. 2008 Nov;62(5):921-8

Chemoprophylaxis is recommended during pregnancy to reduce the risk of placental infection. However, in areas with increasing drug resistance, it can trigger selection of resistant parasites in the placenta and increase the frequency of placental malaria. The objective of this study was to analyse the selection of drug-resistant parasites in the placenta in an area where chloroquine was still recommended as prophylaxis.