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© Institut Pasteur et Institut Imagine
Scanning electron micrograph of segmented filamentous bacterium (SFB). Segmented filamentous bacteria (SFB) are bacteria from the Clostridiaceae family that colonize the intestines of many species, likely including humans, without causing disease; they live in symbiosis with epithelial cells and are involved in the maturation of intestinal immunity.
Publication : Cell host & microbe

A Lasting Impression: Epigenetic Memory of Bacterial Infections?

Team: Chromatin and Infection
Member: Mélanie Hamon
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell host & microbe - 11 May 2016

Pereira JM, Hamon MA, Cossart P

Link to Pubmed [PMID] – 27173925

Cell Host Microbe 2016 May;19(5):579-82

Bacteria can reprogram host gene expression during infection, often through epigenomic mechanisms. However, the lasting impact of such effects remains understudied. This forum discusses examples suggesting that bacterial infection can result in long-lasting memory encoded in epigenomic mechanisms and speculates on the potential of others.