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  • Director of Center
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© Research
Publication : Cell

A Global Effort to Define the Human Genetics of Protective Immunity to SARS-CoV-2 Infection.

Team: Human Evolutionary Genetics
Member: Lluis Quintana-Murci
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Cell - 11 Jun 2020

Casanova JL, Su HC, ,

Link to Pubmed [PMID] – 32405102

Link to DOI – S0092-8674(20)30611-510.1016/j.cell.2020.05.016

Cell 2020 06; 181(6): 1194-1199

SARS-CoV-2 infection displays immense inter-individual clinical variability, ranging from silent infection to lethal disease. The role of human genetics in determining clinical response to the virus remains unclear. Studies of outliers-individuals remaining uninfected despite viral exposure and healthy young patients with life-threatening disease-present a unique opportunity to reveal human genetic determinants of infection and disease.