• 2025
  Adeline Pastuszka, Maria-Vittoria Mazzuoli, Chiara Crestani, Léonie Deborde, Odile Sismeiro, Coralie Lemaire, Vanessa Rong, Myriam Gominet, Elise Jacquemet, Rachel Legendre, Philippe Lanotte, Arnaud Firon, The virulence regulator CovR boosts CRISPR-Cas9 immunity in Group B Streptococcus, Nature Communications, 2025, 16 (1), pp.5678. ⟨10.1038/s41467-025-60871-6⟩.
• 2024
  Claverie C, Coppolino F, Mazzuoli MV, Guyonnet C, Jacquemet E, Legendre R, Sismeiro O, De Gaetano GV, Teti G, Trieu-Cuot P, Tazi A, Beninati C, Firon A, Constitutive activation of two-component systems reveals regulatory network interactions in Streptococcus agalactiae., Nat Commun 2024 Oct; 15(1): 9175.
• 2024
  Lorga I, Geraldo R, Soares J, Oliveira L, Firon A, Bonifácio Andrade E, Development of bioluminescent Group B streptococcal strains for longitudinal infection studies., Sci Rep 2024 Oct; 14(1): 24439.
• 2024
  Coppolino F, De Gaetano GV, Claverie C, Sismeiro O, Varet H, Legendre R, Pellegrini A, Berbiglia A, Tavella L, Lentini G, Famà A, Barbieri G, Pietrocola G, Teti G, Firon A, Beninati C, The SaeRS two-component system regulates virulence gene expression in group B Streptococcus during invasive infection., mBio 2024 Sep; 15(9): e0197524.
• 2024
  Caliot E, Firon A, Solgadi A, Trieu-Cuot P, Dramsi S, Lipid lysination by MprF contributes to hemolytic pigment retention in group B Streptococcus., Res Microbiol 2024 Aug; (): 104231.
• 2024
  Brissac T, Guyonnet C, Sadouni A, Hernández-Montoya A, Jacquemet E, Legendre R, Sismeiro O, Trieu-Cuot P, Lanotte P, Tazi A, Firon A, Coordinated regulation of osmotic imbalance by c-di-AMP shapes ß-lactam tolerance in Group B Streptococcus., Microlife 2024 ; 5(): uqae014.
• 2023
  Covaleda-Cortés G, Mechaly A, Brissac T, Baehre H, Devaux L, England P, Raynal B, Hoos S, Gominet M, Firon A, Trieu-Cuot P, Kaminski PA, , The c-di-AMP-binding protein CbpB modulates the level of ppGpp alarmone in Streptococcus agalactiae., FEBS J 2023 Jan; (): .
• 2022
  Pellegrini A, Lentini G, Famà A, Bonacorsi A, Scoffone VC, Buroni S, Trespidi G, Postiglione U, Sassera D, Manai F, Pietrocola G, Firon A, Biondo C, Teti G, Beninati C, Barbieri G, , CodY Is a Global Transcriptional Regulator Required for Virulence in Group B Streptococcus., Front Microbiol 2022 ; 13: 881549.
• 2021
  Mazzuoli MV, Daunesse M, Varet H, Rosinski-Chupin I, Legendre R, Sismeiro O, Gominet M, Kaminski PA, Glaser P, Chica C, Trieu-Cuot P, Firon A, , The CovR regulatory network drives the evolution of Group B Streptococcus virulence., PLoS Genet 2021 Sep; 17(9): e1009761.
• 2021
  Jung YJ, Huynh BT, Seck A, Bercion R, Sarr FD, Herindrainy P, Diouf JB, Andrianirina ZZ, Firon A, Trieu-Cuot P, Goyet S, Collard JM, Delaroque-Astagneau E, Guillemot D, Vray M, , , Prevalence and Factors Associated with Maternal Group B Streptococcus Colonization in Madagascar and Senegal., Am J Trop Med Hyg 2021 Aug; (): .
• 2018
  Lentini G, Midiri A, Firon A, Galbo R, Mancuso G, Biondo C, Mazzon E, Passantino A, Romeo L, Trieu-Cuot P, Teti G, Beninati C, The plasminogen binding protein PbsP is required for brain invasion by hypervirulent CC17 Group B streptococci, Sci Rep 2018 Sep;8(1):14322.
• 2018
  Andrade EB, Magalhães A, Puga A, Costa M, Bravo J, Portugal CC, Ribeiro A, Correia-Neves M, Faustino A, Firon A, Trieu-Cuot P, Summavielle T, Ferreira P, A mouse model reproducing the pathophysiology of neonatal group B streptococcal infection, Nat Commun 2018 Aug;9(1):3138.
• 2018
  De Gaetano GV, Pietrocola G, Romeo L, Galbo R, Lentini G, Giardina M, Biondo C, Midiri A, Mancuso G, Venza M, Venza I, Firon A, Trieu-Cuot P, Teti G, Speziale P, Beninati C, The Streptococcus agalactiae cell wall-anchored protein PbsP mediates adhesion to and invasion of epithelial cells by exploiting the host vitronectin/α integrin axis, Mol. Microbiol. 2018 Jul;.
• 2018
  Devaux L, Sleiman D, Mazzuoli MV, Gominet M, Lanotte P, Trieu-Cuot P, Kaminski PA, Firon A, Cyclic di-AMP regulation of osmotic homeostasis is essential in Group B Streptococcus, PLoS Genet. 2018 Apr;14(4):e1007342.
• 2017
  Devaux L, Kaminski PA, Trieu-Cuot P, Firon A, Cyclic di-AMP in host-pathogen interactions, Curr. Opin. Microbiol. 2018 Feb;41:21-28.
• 2016
  Andrade WA, Firon A, Schmidt T, Hornung V, Fitzgerald KA, Kurt-Jones EA, Trieu-Cuot P, Golenbock DT, Kaminski PA, Group B Streptococcus Degrades Cyclic-di-AMP to Modulate STING-Dependent Type I Interferon Production, Cell Host Microbe 2016 Jul;20(1):49-59.
• 2016
  Buscetta M, Firon A, Pietrocola G, Biondo C, Mancuso G, Midiri A, Romeo L, Galbo R, Venza M, Venza I, Kaminski PA, Gominet M, Teti G, Speziale P, Trieu-Cuot P, Beninati C, PbsP, a cell wall-anchored protein that binds plasminogen to promote hematogenous dissemination of group B Streptococcus, Mol. Microbiol. 2016 Jul;101(1):27-41.
• 2016
  Six A, Firon A, Plainvert C, Caplain C, Touak G, Dmytruk N, Longo M, Letourneur F, Fouet A, Trieu-Cuot P, Poyart C, Molecular Characterization of Nonhemolytic and Nonpigmented Group B Streptococci Responsible for Human Invasive Infections, J. Clin. Microbiol. 2016 Jan;54(1):75-82.
• 2014
  Buscetta M, Papasergi S, Firon A, Pietrocola G, Biondo C, Mancuso G, Midiri A, Romeo L, Teti G, Speziale P, Trieu-Cuot P, Beninati C, FbsC, a novel fibrinogen-binding protein, promotes Streptococcus agalactiae-host cell interactions, J. Biol. Chem. 2014 Jul;289(30):21003-21015.
• 2014
  Schwarzmüller T, Ma B, Hiller E, Istel F, Tscherner M, Brunke S, Ames L, Firon A, Green B, Cabral V, Marcet-Houben M, Jacobsen ID, Quintin J, Seider K, Frohner I, Glaser W, Jungwirth H, Bachellier-Bassi S, Chauvel M, Zeidler U, Ferrandon D, Gabaldón T, Hube B, d'Enfert C, Rupp S, Cormack B, Haynes K, Kuchler K, Systematic phenotyping of a large-scale Candida glabrata deletion collection reveals novel antifungal tolerance genes, PLoS Pathog. 2014 Jun;10(6):e1004211.
• 2014
  Gupta R, Ghosh S, Monks B, DeOliveira RB, Tzeng TC, Kalantari P, Nandy A, Bhattacharjee B, Chan J, Ferreira F, Rathinam V, Sharma S, Lien E, Silverman N, Fitzgerald K, Firon A, Trieu-Cuot P, Henneke P, Golenbock DT, RNA and β-hemolysin of group B Streptococcus induce interleukin-1β (IL-1β) by activating NLRP3 inflammasomes in mouse macrophages, J. Biol. Chem. 2014 May;289(20):13701-5.
• 2014
  Firon A, Dinis M, Raynal B, Poyart C, Trieu-Cuot P, Kaminski PA, Extracellular nucleotide catabolism by the Group B Streptococcus ectonucleotidase NudP increases bacterial survival in blood, J. Biol. Chem. 2014 Feb;289(9):5479-89.
• 2013
  Gastebois A, Aimanianda V, Bachellier-Bassi S, Nesseir A, Firon A, Beauvais A, Schmitt C, England P, Beau R, Prévost MC, d'Enfert C, Latgé JP, Mouyna I, SUN proteins belong to a novel family of β-(1,3)-glucan-modifying enzymes involved in fungal morphogenesis, J. Biol. Chem. 2013 May;288(19):13387-96.
• 2013
  Firon A, Tazi A, Da Cunha V, Brinster S, Sauvage E, Dramsi S, Golenbock DT, Glaser P, Poyart C, Trieu-Cuot P, The Abi-domain protein Abx1 interacts with the CovS histidine kinase to control virulence gene expression in group B Streptococcus, PLoS Pathog. 2013 Feb;9(2):e1003179.
• 2012
  Saar-Dover R, Bitler A, Nezer R, Shmuel-Galia L, Firon A, Shimoni E, Trieu-Cuot P, Shai Y, D-alanylation of lipoteichoic acids confers resistance to cationic peptides in group B streptococcus by increasing the cell wall density, PLoS Pathog. 2012 Sep;8(9):e1002891.
• 2012
  Grohs P, Trieu-Cuot P, Podglajen I, Grondin S, Firon A, Poyart C, Varon E, Gutmann L, Molecular basis for different levels of tet(M) expression in Streptococcus pneumoniae clinical isolates, Antimicrob. Agents Chemother. 2012 Oct;56(10):5040-5.
• 2012
  Cabral V, Chauvel M, Firon A, Legrand M, Nesseir A, Bachellier-Bassi S, Chaudhari Y, Munro CA, d'Enfert C, Modular gene over-expression strategies for Candida albicans, Methods Mol. Biol. 2012;845:227-44.
• 2011
  Papasergi S, Brega S, Mistou MY, Firon A, Oxaran V, Dover R, Teti G, Shai Y, Trieu-Cuot P, Dramsi S, The GBS PI-2a pilus is required for virulence in mice neonates, PLoS ONE 2011;6(4):e18747.
• 2009
  Jacobsen ID, Brunke S, Seider K, Schwarzmüller T, Firon A, d'Enfért C, Kuchler K, Hube B, Candida glabrata persistence in mice does not depend on host immunosuppression and is unaffected by fungal amino acid auxotrophy, Infect. Immun. 2010 Mar;78(3):1066-77.
• 2007
  Firon A, Aubert S, Iraqui I, Guadagnini S, Goyard S, Prévost MC, Janbon G, d'Enfert C, The SUN41 and SUN42 genes are essential for cell separation in Candida albicans, Mol. Microbiol. 2007 Dec;66(5):1256-75.
• 2004
  Firon A, Lesage G, Bussey H, Integrative studies put cell wall synthesis on the yeast functional map, Curr. Opin. Microbiol. 2004 Dec;7(6):617-23.
• 2003
  Firon A, Villalba F, Beffa R, D'Enfert C, Identification of essential genes in the human fungal pathogen Aspergillus fumigatus by transposon mutagenesis, Eukaryotic Cell 2003 Apr;2(2):247-55.
• 2002
  Firon A, d'Enfert C, Identifying essential genes in fungal pathogens of humans, Trends Microbiol. 2002 Oct;10(10):456-62.
• 2002
  Firon A, Beauvais A, Latgé JP, Couvé E, Grosjean-Cournoyer MC, D'Enfert C, Characterization of essential genes by parasexual genetics in the human fungal pathogen Aspergillus fumigatus: impact of genomic rearrangements associated with electroporation of DNA, Genetics 2002 Jul;161(3):1077-87.