• 2023
  Yann Aquino, Aurélie Bisiaux, Zhi Li, Mary O'Neill, Javier Mendoza-Revilla, Sarah Hélène Merkling, Gaspard Kerner, Milena Hasan, Valentina Libri, Vincent Bondet, Nikaïa Smith, Camille de Cevins, Mickaël Ménager, Francesca Luca, Roger Pique-Regi, Giovanna Barba-Spaeth, Stefano Pietropaoli, Olivier Schwartz, Geert Leroux-Roels, Cheuk-Kwong Lee, Kathy Leung, Joseph Wu, Malik Peiris, Roberto Bruzzone, Laurent Abel, Jean-Laurent Casanova, Sophie Valkenburg, Darragh Duffy, Etienne Patin, Maxime Rotival, Lluis Quintana-Murci, Dissecting human population variation in single-cell responses to SARS-CoV-2, Nature, 2023, 53 (8), pp.e2250307. ⟨10.1038/s41586-023-06422-9⟩.
• 2023
  Bekaddour N, Smith N, Beitz B, Llibre A, Dott T, Baudry A, Korganow AS, Nisole S, Mouy R, Breton S, Bader-Meunier B, Duffy D, Terrier B, Schneider B, Quartier P, Rodero MP, Herbeuval JP, Targeting the chemokine receptor CXCR4 with histamine analog to reduce inflammation in juvenile arthritis., Front Immunol 2023 ; 14(): 1178172.
• 2022
  Smith N, Possémé C, Bondet V, Sugrue J, Townsend L, Charbit B, Rouilly V, Saint-André V, Dott T, Pozo AR, Yatim N, Schwartz O, Cervantes-Gonzalez M, Ghosn J, Bastard P, Casanova JL, Szwebel TA, Terrier B, Conlon N, O'Farrelly C, Cheallaigh CN, Bourke NM, Duffy D, Defective activation and regulation of type I interferon immunity is associated with increasing COVID-19 severity., Nat Commun 2022 Nov; 13(1): 7254.
• 2022
  Posseme C, Llibre A, Charbit B, Bondet V, Rouilly V, Saint-André V, Boussier J, Bergstedt J, Smith N, Townsend L, Sugrue JA, Ní Cheallaigh C, Conlon N, Rotival M, Kobor MS, Mottez E, Pol S, Patin E, Albert ML, Quintana-Murci L, Duffy D, Early IFNβ secretion determines variable downstream IL-12p70 responses upon TLR4 activation., Cell Rep 2022 Jun; 39(13): 110989.
• 2022
  Llibre A, Smith N, Rouilly V, Musvosvi M, Nemes E, Posseme C, Mabwe S, Charbit B, Mbandi SK, Filander E, Africa H, Saint-André V, Bondet V, Bost P, Mulenga H, Bilek N, Albert ML, Scriba TJ, Duffy D, , Tuberculosis alters immune-metabolic pathways resulting in perturbed IL-1 responses., Front Immunol 2022 ; 13(): 897193.
• 2021
  Frumholtz L, Bouaziz JD, Battistella M, Hadjadj J, Chocron R, Bengoufa D, Le Buanec H, Barnabei L, Meynier S, Schwartz O, Grzelak L, Smith N, Charbit B, Duffy D, Yatim N, Calugareanu A, Philippe A, Guerin CL, Joly B, Siguret V, Jaume L, Bachelez H, Bagot M, Rieux-Laucat F, Maylin S, Legoff J, Delaugerre C, Gendron N, Smadja DM, Cassius C, , , Type I interferon response and vascular alteration in chilblain-like lesions during the COVID-19 outbreak., Br J Dermatol 2021 12; 185(6): 1176-1185.
• 2021
  Monel B, Planas D, Grzelak L, Smith N, Robillard N, Staropoli I, Goncalves P, Porrot F, Guivel-Benhassine F, Guinet ND, Rodary J, Puech J, Euzen V, Bélec L, Orvoen G, Nunes L, Moulin V, Fourgeaud J, Wack M, Imbeaud S, Campagne P, Duffy D, Santo JPD, Bruel T, Péré H, Veyer D, Schwartz O, , Release of infectious virus and cytokines in nasopharyngeal swabs from individuals infected with non-alpha or alpha SARS-CoV-2 variants: an observational retrospective study., EBioMedicine 2021 Nov; 73(): 103637.
• 2021
  Smith N, Goncalves P, Charbit B, Grzelak L, Beretta M, Planchais C, Bruel T, Rouilly V, Bondet V, Hadjadj J, Yatim N, Pere H, Merkling SH, Ghozlane A, Kernéis S, Rieux-Laucat F, Terrier B, Schwartz O, Mouquet H, Duffy D, Di Santo JP, , Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection., Nat Immunol 2021 Sep; 22(11):1428-1439.
• 2021
  Yatim N, Boussier J, Tetu P, Smith N, Bruel T, Charbit B, Barnabei L, Corneau A, Da Meda L, Allayous C, Baroudjian B, Jebali M, Herms F, Grzelak L, Staropoli I, Calmettes V, Hadjadj J, Peyrony O, Cassius C, LeGoff J, Kramkimel N, Aractingi S, Fontes M, Blanc C, Rieux-Laucat F, Schwartz O, Terrier B, Duffy D, Lebbé C, , Immune checkpoint inhibitors increase T cell immunity during SARS-CoV-2 infection., Sci Adv 2021 08; 7(34): .
• 2021
  Robinot R, Hubert M, de Melo GD, Lazarini F, Bruel T, Smith N, Levallois S, Larrous F, Fernandes J, Gellenoncourt S, Rigaud S, Gorgette O, Thouvenot C, Trébeau C, Mallet A, Duménil G, Gobaa S, Etournay R, Lledo PM, Lecuit M, Bourhy H, Duffy D, Michel V, Schwartz O, Chakrabarti LA, SARS-CoV-2 infection induces the dedifferentiation of multiciliated cells and impairs mucociliary clearance., Nat Commun 2021 Jul; 12(1): 4354.
• 2020
  Duffy D, Nemes E, Llibre A, Rouilly V, Musvosvi M, Smith N, Filander E, Africa H, Mabwe S, Jaxa L, Charbit B, Mulenga H, Tameris M, Walzl G, Malherbe S, Thomas S, Hatherill M, Bilek N, Scriba TJ, Albert ML, Immune Profiling Enables Stratification of Patients With Active Tuberculosis Disease or Mycobacterium tuberculosis Infection., Clin Infect Dis 2021 Nov; 73(9): e3398-e3408.
• 2020
  Rivière E, Pascaud J, Virone A, Dupré A, Ly B, Paoletti A, Seror R, Tchitchek N, Mingueneau M, Smith N, Duffy D, Cassard L, Chaput N, Pengam S, Gauttier V, Poirier N, Mariette X, Nocturne G, , Interleukin-7/Interferon axis drives T-cell and salivary gland epithelial cell interactions in Sjögren’s syndrome., Arthritis Rheumatol 2020 Oct; (): .
• 2020
  Hadjadj J, Yatim N, Barnabei L, Corneau A, Boussier J, Smith N, Péré H, Charbit B, Bondet V, Chenevier-Gobeaux C, Breillat P, Carlier N, Gauzit R, Morbieu C, Pène F, Marin N, Roche N, Szwebel TA, Merkling SH, Treluyer JM, Veyer D, Mouthon L, Blanc C, Tharaux PL, Rozenberg F, Fischer A, Duffy D, Rieux-Laucat F, Kernéis S, Terrier B, , Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients., Science 2020 08; 369(6504): 718-724.
• 2020
  Upasani V, Scagnolari C, Frasca F, Smith N, Bondet V, Vanderlinden A, Lay S, Auerswald H, Heng S, Laurent D, Ly S, Duong V, Antonelli G, Dussart P, Duffy D, Cantaert T, , Decreased Type I Interferon Production by Plasmacytoid Dendritic Cells Contributes to Severe Dengue., Front Immunol 2020 ; 11(): 605087.
• 2019
  Smith N, Rodero MP, Bekaddour N, Bondet V, Ruiz-Blanco YB, Harms M, Mayer B, Badder-Meunier B, Quartier P, Bodemer C, Baudouin V, Dieudonné Y, Kirchhoff F, Sanchez Garcia E, Charbit B, Leboulanger N, Jahrsdörfer B, Richard Y, Korganow AS, Münch J, Nisole S, Duffy D, Herbeuval JP, Control of TLR7-mediated type I IFN signaling in pDCs through CXCR4 engagement-A new target for lupus treatment, Sci Adv 2019 Jul;5(7):eaav9019.
• 2019
  Langer S, Hammer C, Hopfensperger K, Klein L, Hotter D, De Jesus PD, Herbert KM, Pache L, Smith N, van der Merwe JA, Chanda SK, Fellay J, Kirchhoff F, Sauter D, HIV-1 Vpu is a potent transcriptional suppressor of NF-κB-elicited antiviral immune responses, Elife 2019 Feb;8.
• 2019
  Krüger F, Kumar V, Monge P, Conzelmann C, Smith N, Gothelf KV, Tolstrup M, Münch J, Zelikin AN, Nucleic Acids as a Nature-Inspired Scaffold for Macromolecular Prodrugs of Nucleoside Analogues, Adv Sci (Weinh) 2019 Mar;6(6):1802095.
• 2018
  Hayek S, Bekaddour N, Besson L, Alves de Sousa R, Pietrancosta N, Viel S, Smith N, Jacob Y, Nisole S, Mandal R, Wishart DS, Walzer T, Herbeuval JP, Vidalain PO, Identification of Primary Natural Killer Cell Modulators by Chemical Library Screening with a Luciferase-Based Functional Assay, SLAS Discov 2019 Jan;24(1):25-37.
• 2018
  Sinigaglia L, Gracias S, Décembre E, Fritz M, Bruni D, Smith N, Herbeuval JP, Martin A, Dreux M, Tangy F, Jouvenet N, , Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons., Sci Rep 2018 Jul; 8(1): 10889.
• 2017
  Smith N, Pietrancosta N, Herbeuval JP, [CXCR4, master regulator of innate immune responses?], Med Sci (Paris) 2017 Aug-Sep;33(8-9):711-713.
• 2017
  Allam A, Maigre L, Vergalli J, Dumont E, Cinquin B, Alves de Sousa R, Pajovic J, Pinet E, Smith N, Herbeuval JP, Réfrégiers M, Artaud I, Pagès JM, Microspectrofluorimetry to dissect the permeation of ceftazidime in Gram-negative bacteria, Sci Rep 2017 04;7(1):986.
• 2017
  Smith N, Pietrancosta N, Davidson S, Dutrieux J, Chauveau L, Cutolo P, Dy M, Scott-Algara D, Manoury B, Zirafi O, McCort-Tranchepain I, Durroux T, Bachelerie F, Schwartz O, Münch J, Wack A, Nisole S, Herbeuval JP, Natural amines inhibit activation of human plasmacytoid dendritic cells through CXCR4 engagement, Nat Commun 2017 02;8:14253.
• 2016
  Smith N, Vidalain PO, Nisole S, Herbeuval JP, An efficient method for gene silencing in human primary plasmacytoid dendritic cells: silencing of the TLR7/IRF-7 pathway as a proof of concept, Sci Rep 2016 07;6:29891.
• 2016
  Borhis G, Burelout C, Chaoul N, Smith N, Goujard C, Meyer L, Paul S, Saoudin H, Hosmalin A, Gilbert C, Herbeuval JP, Richard Y, Plasmacytoid dendritic cells and myeloid cells differently contribute to B-cell-activating factor belonging to the tumor necrosis factor superfamily overexpression during primary HIV infection, AIDS 2016 Jan;30(3):365-76.
• 2015
  Griesbeck M, Ziegler S, Laffont S, Smith N, Chauveau L, Tomezsko P, Sharei A, Kourjian G, Porichis F, Hart M, Palmer CD, Sirignano M, Beisel C, Hildebrandt H, Cénac C, Villani AC, Diefenbach TJ, Le Gall S, Schwartz O, Herbeuval JP, Autran B, Guéry JC, Chang JJ, Altfeld M, Sex Differences in Plasmacytoid Dendritic Cell Levels of IRF5 Drive Higher IFN-α Production in Women, J. Immunol. 2015 Dec;195(11):5327-36.
• 2015
  Smith N, Herbeuval JP, [Plasmacytoid dendritic cells: the novel Eldorado for antiviral therapy?], Biol Aujourdhui 2015;209(2):135-44.
• 2015
  Smith N, Etheve-Quelquejeu M, Herbeuval JP, Transformation of Plasmacytoid Dendritic Cells into Giant Multinuclear Cells by HIV-1, AIDS Res. Hum. Retroviruses 2015 Oct;31(10):959-60.
• 2015
  Dao P, Smith N, Scott-Algara D, Garbay C, Herbeuval JP, Chen H, Restoration of TRAIL-induced apoptosis in resistant human pancreatic cancer cells by a novel FAK inhibitor, PH11, Cancer Lett. 2015 Apr;360(1):48-59.
• 2014
  Smith N, Etheve-Quelquejeu M, Herbeuval JP, CD4 and Tumor Necrosis Factor-Related Apoptosis Ligand (TRAIL) localization in HIV-stimulated plasmacytoid dendritic cells by three-dimensional microscopy, AIDS Res. Hum. Retroviruses 2014 Dec;30(12):1158-9.
• 2014
  Dao P, Smith N, Tomkiewicz-Raulet C, Yen-Pon E, Camacho-Artacho M, Lietha D, Herbeuval JP, Coumoul X, Garbay C, Chen H, Design, synthesis, and evaluation of novel imidazo[1,2-a][1,3,5]triazines and their derivatives as focal adhesion kinase inhibitors with antitumor activity, J. Med. Chem. 2015 Jan;58(1):237-51.
• 2014
  Barblu L, Smith N, Durand S, Scott-Algara D, Boufassa F, Delfraissy JF, Cimarelli A, Lambotte O, Herbeuval JP, Reduction of death receptor 5 expression and apoptosis of CD4+ T cells from HIV controllers, Clin. Immunol. 2014 Nov;155(1):17-26.
• 2014
  Dao P, Jarray R, Smith N, Lepelletier Y, Le Coq J, Lietha D, Hadj-Slimane R, Herbeuval JP, Garbay C, Raynaud F, Chen H, Inhibition of both focal adhesion kinase and fibroblast growth factor receptor 2 pathways induces anti-tumor and anti-angiogenic activities, Cancer Lett. 2014 Jun;348(1-2):88-99.
• 2013
  Gandini M, Gras C, Azeredo EL, Pinto LM, Smith N, Despres P, da Cunha RV, de Souza LJ, Kubelka CF, Herbeuval JP, Dengue virus activates membrane TRAIL relocalization and IFN-α production by human plasmacytoid dendritic cells in vitro and in vivo, PLoS Negl Trop Dis 2013;7(6):e2257.
• 2012
  Herbeuval JP, Smith N, Thèze J, Characteristics of plasmacytoid dendritic cell and CD4+ T cell in HIV elite controllers, Clin. Dev. Immunol. 2012;2012:869505.
• 2012
  Gras C, Smith N, Sengmanivong L, Gandini M, Kubelka CF, Herbeuval JP, TRAIL protein localization in human primary T cells by 3D microscopy using 3D interactive surface plot: a new method to visualize plasma membrane, J. Immunol. Methods 2013 Jan;387(1-2):147-56.