-
2024A host-directed oxadiazole compound potentiates antituberculosis treatment via zinc poisoning in human macrophages and in a mouse model of infection., PLoS Biol 2024 Apr; 22(4): e3002259.
-
2021De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis., Elife 2021 Dec; 10(): .
-
2021ESX-1-Independent Horizontal Gene Transfer by Mycobacterium tuberculosis Complex Strains, mBio, 2021, 12 (3), ⟨10.1128/mBio.00965-21⟩.
-
2021Pathogenomic analyses of Mycobacterium microti, an ESX-1-deleted member of the Mycobacterium tuberculosis complex causing disease in various hosts., Microb Genom 2021 02; 7(2): .
-
2020Live attenuated TB vaccines representing the three modern Mycobacterium tuberculosis lineages reveal that the Euro-American genetic background confers optimal vaccine potential, EBioMedicine 2020 Apr;55:102761.
-
2020Discovery of a novel dehydratase of the fatty acid synthase type II critical for ketomycolic acid biosynthesis and virulence of Mycobacterium tuberculosis, Sci Rep 2020 Feb;10(1):2112.
-
2020TbD1 deletion as a driver of the evolutionary success of modern epidemic Mycobacterium tuberculosis lineages, Nat Commun 2020 Feb;11(1):684.
-
2019Mycobacterial virulence: impact on immunogenicity and vaccine research, F1000Res 2019;8.
-
2018RD5-mediated lack of PE_PGRS and PPE-MPTR export in BCG vaccine strains results in strong reduction of antigenic repertoire but little impact on protection, PLoS Pathog. 2018 Jun;14(6):e1007139.
-
2018Multiplexed Quantitation of Intraphagocyte Mycobacterium tuberculosis Secreted Protein Effectors, Cell Rep 2018 Apr;23(4):1072-1084.
-
2017PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis., PLoS Pathog 2017 May; 13(5): e1006399.
-
2017Recombinant BCG Expressing ESX-1 of Mycobacterium marinum Combines Low Virulence with Cytosolic Immune Signaling and Improved TB Protection, Cell Reports 2017, 18, (11), 2752–2765.
-
2016CD4+ T Cells Recognizing PE/PPE Antigens Directly or via Cross Reactivity Are Protective against Pulmonary Mycobacterium tuberculosis Infection, PLoS Pathog. 2016 Jul 28;12(7):e1005770. doi: 10.1371/journal.ppat.1005770..
-
2016pks5-recombination-mediated surface remodelling in Mycobacterium tuberculosis emergence, Nature Microbiol. 1, 15019 (2016).
-
2015Revisiting the role of phospholipases C in virulence and the lifecycle of Mycobacterium tuberculosis, Sci Rep 2015;5:16918.
-
2015The changes in mycolic acid structures caused by hadC mutation have a dramatic effect on the virulence of Mycobacterium tuberculosis, Mol. Microbiol. 2015 Nov;.
-
2015Increased protective efficacy of recombinant BCG strains expressing virulence-neutral proteins of the ESX-1 secretion system, Vaccine 2015 May;33(23):2710-8.
-
2015ESX/type VII secretion systems of mycobacteria: Insights into evolution, pathogenicity and protection, Tuberculosis (Edinb) 2015 Feb;.
-
2014A specific polymorphism in Mycobacterium tuberculosis H37Rv causes differential ESAT-6 expression and identifies WhiB6 as a novel ESX-1 component, Infect. Immun. 2014 Aug;82(8):3446-56.
-
2013Genomic analysis of smooth tubercle bacilli provides insights into ancestry and pathoadaptation of Mycobacterium tuberculosis, Nat. Genet. 2013 Feb;45(2):172-9.