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Guides
  • 2023
    Prevost MS, Barilone N, Dejean de la Bâtie G, Pons S, Ayme G, England P, Gielen M, Bontems F, Pehau-Arnaudet G, Maskos U, Lafaye P, Corringer PJ, An original potentiating mechanism revealed by the cryo-EM structures of the human α7 nicotinic receptor in complex with nanobodies., Nat Commun 2023 Sep; 14(1): 5964.
  • 2023
    Li Q, Nemecz Á, Aymé G, Dejean de la Bâtie G, Prevost MS, Pons S, Barilone N, Baachaoui R, Maskos U, Lafaye P, Corringer PJ, Generation of nanobodies acting as silent and positive allosteric modulators of the α7 nicotinic acetylcholine receptor., Cell Mol Life Sci 2023 May; 80(6): 164.
  • 2020
    Gielen M, Barilone N, Corringer PJ, , The desensitization pathway of GABAA receptors, one subunit at a time., Nat Commun 2020 10; 11(1): 5369.
  • 2017
    Lisa MN, Wagner T, Alexandre M, Barilone N, Raynal B, Alzari PM, Bellinzoni M, , The crystal structure of PknI from Mycobacterium tuberculosis shows an inactive, pseudokinase-like conformation., FEBS J 2017 02; 284(4): 602-614.
  • 2015
    Mori G, Chiarelli LR, Esposito M, Makarov V, Bellinzoni M, Hartkoorn RC, Degiacomi G, Boldrin F, Ekins S, de Jesus Lopes Ribeiro AL, Marino LB, Centárová I, Svetlíková Z, Blaško J, Kazakova E, Lepioshkin A, Barilone N, Zanoni G, Porta A, Fondi M, Fani R, Baulard AR, Mikušová K, Alzari PM, Manganelli R, de Carvalho LP, Riccardi G, Cole ST, Pasca MR, , Thiophenecarboxamide Derivatives Activated by EthA Kill Mycobacterium tuberculosis by Inhibiting the CTP Synthetase PyrG., Chem Biol 2015 Jul; 22(7): 917-27.
  • 2015
    Wagner T, Alexandre M, Duran R, Barilone N, Wehenkel A, Alzari PM, Bellinzoni M, , The crystal structure of the catalytic domain of the ser/thr kinase PknA from M. tuberculosis shows an Src-like autoinhibited conformation., Proteins 2015 May; 83(5): 982-8.
  • 2014
    Giganti D, Albesa-Jové D, Urresti S, Rodrigo-Unzueta A, Martínez MA, Comino N, Barilone N, Bellinzoni M, Chenal A, Guerin ME, Alzari PM, , Secondary structure reshuffling modulates glycosyltransferase function at the membrane., Nat Chem Biol 2015 Jan; 11(1): 16-8.
  • 2012
    Mechaly AE, Haouz A, Miras I, Barilone N, Weber P, Shepard W, Alzari PM, Bellinzoni M, , Conformational changes upon ligand binding in the essential class II fumarase Rv1098c from Mycobacterium tuberculosis., FEBS Lett 2012 Jun; 586(11): 1606-11.
  • 2010
    Skovierová H, Larrouy-Maumus G, Pham H, Belanová M, Barilone N, Dasgupta A, Mikusová K, Gicquel B, Gilleron M, Brennan PJ, Puzo G, Nigou J, Jackson M, Biosynthetic origin of the galactosamine substituent of Arabinogalactan in Mycobacterium tuberculosis, J. Biol. Chem. 2010 Dec;285(53):41348-55.
  • 2010
    Minime-Lingoupou F, Pierre-Audigier C, Kassa-Kélémbho E, Barilone N, Zandanga G, Rauzier J, Cadet-Daniel V, Le Faou A, Gicquel B, Rapid identification of multidrug-resistant tuberculosis isolates in treatment failure or relapse patients in Bangui, Central African Republic, Int. J. Tuberc. Lung Dis. 2010 Jun;14(6):782-5.
  • 2009
    Skovierová H, Larrouy-Maumus G, Zhang J, Kaur D, Barilone N, Korduláková J, Gilleron M, Guadagnini S, Belanová M, Prevost MC, Gicquel B, Puzo G, Chatterjee D, Brennan PJ, Nigou J, Jackson M, AftD, a novel essential arabinofuranosyltransferase from mycobacteria, Glycobiology 2009 Nov;19(11):1235-47.
  • 2008
    Sambou T, Dinadayala P, Stadthagen G, Barilone N, Bordat Y, Constant P, Levillain F, Neyrolles O, Gicquel B, Lemassu A, Daffé M, Jackson M, Capsular glucan and intracellular glycogen of Mycobacterium tuberculosis: biosynthesis and impact on the persistence in mice, Mol. Microbiol. 2008 Nov;70(3):762-74.
  • 2008
    Fonvielle M, Coinçon M, Daher R, Desbenoit N, Kosieradzka K, Barilone N, Gicquel B, Sygusch J, Jackson M, Therisod M, Synthesis and biochemical evaluation of selective inhibitors of class II fructose bisphosphate aldolases: towards new synthetic antibiotics, Chemistry 2008;14(28):8521-9.
  • 2007
    Stadthagen G, Sambou T, Guerin M, Barilone N, Boudou F, Korduláková J, Charles P, Alzari PM, Lemassu A, Daffé M, Puzo G, Gicquel B, Rivière M, Jackson M, Genetic basis for the biosynthesis of methylglucose lipopolysaccharides in Mycobacterium tuberculosis, J. Biol. Chem. 2007 Sep;282(37):27270-6.
  • 2007
    Kordulakova, J.; Janin, Y. L.; Liav, A.; Barilone, N.; Vultos, T. D.; Rauzier, J.; Brennan, P. J.; Gicquel, B.; Jackson, M., Isoxyl activation is required for bacteriostatic activity against Mycobacterium tuberculosis, Antimicrob. Agents Chemother. 2007, 51, 3824-3829.
  • 2006
    Fernandez P, Saint-Joanis B, Barilone N, Jackson M, Gicquel B, Cole ST, Alzari PM, The Ser/Thr protein kinase PknB is essential for sustaining mycobacterial growth, J. Bacteriol. 2006 Nov;188(22):7778-84.
  • 2006
    Stadthagen G, Jackson M, Charles P, Boudou F, Barilone N, Huerre M, Constant P, Liav A, Bottova I, Nigou J, Brando T, Puzo G, Daffé M, Benjamin P, Coade S, Buxton RS, Tascon RE, Rae A, Robertson BD, Lowrie DB, Young DB, Gicquel B, Griffin R, Comparative investigation of the pathogenicity of three Mycobacterium tuberculosis mutants defective in the synthesis of p-hydroxybenzoic acid derivatives, Microbes Infect. 2006 Jul;8(8):2245-53.
  • 2005
    Gonzalo Asensio J, Maia C, Ferrer NL, Barilone N, Laval F, Soto CY, Winter N, Daffé M, Gicquel B, Martín C, Jackson M, The virulence-associated two-component PhoP-PhoR system controls the biosynthesis of polyketide-derived lipids in Mycobacterium tuberculosis, J. Biol. Chem. 2006 Jan;281(3):1313-6.
  • 2005
    Stadthagen G, Korduláková J, Griffin R, Constant P, Bottová I, Barilone N, Gicquel B, Daffé M, Jackson M, p-Hydroxybenzoic acid synthesis in Mycobacterium tuberculosis, J. Biol. Chem. 2005 Dec;280(49):40699-706.
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