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Guides
  • 2025
    Vial T, Lopez-Maestre H, Couderc E, Pinaud S, Howick V, Akorli J, Lawniczak M, Marti G, Merkling SH, Single-cell transcriptional landscapes of Aedes aegypti midgut and fat body after a bloodmeal., Cell Genom 2025 Aug; 5(8): 100924.
  • 2025
    Sarah H Merkling, Elodie Couderc, Anna B Crist, Stéphanie Dabo, Josquin Daron, Natapong Jupatanakul, Myriam Burckbuchler, Thomas Vial, Odile Sismeiro, Rachel Legendre, Adrien Pain, Hugo Varet, Davy Jiolle, Diego Ayala, Christophe Paupy, Eric Marois, Louis Lambrechts, Dengue virus susceptibility in Aedes aegypti linked to natural cytochrome P450 promoter variants, Nature Communications, 2025, 16 (1), pp.7468. ⟨10.1038/s41467-025-62693-y⟩.
  • 2025
    Elodie Couderc, Anna B Crist, Josquin Daron, Hugo Varet, Femke a H van Hout, Pascal Miesen, Umberto Palatini, Stéphanie Dabo, Thomas Vial, Louis Lambrechts, Sarah H Merkling, Aedes aegypti VLG-1 challenges the assumed antiviral nature of Vago genes, BMC Biology, 2025, 23 (1), pp.223. ⟨10.1186/s12915-025-02325-5⟩.
  • 2025
    Alexander Bergman, Anna Crist, Hélène Lopez-Maestre, Hervé Blanc, Mauro Castelló-Sanjuán, Lionel Frangeul, Hugo Varet, Josquin Daron, Sarah Hélène Merkling, Maria-Carla P Saleh, Louis A Lambrechts, Limited impact of the siRNA pathway on transposable element expression in Aedes aegypti, BMC Biology, 2025, 23 (1), pp.130. ⟨10.1186/s12915-025-02225-8⟩.
  • 2023
    Merkling SH, Crist AB, Henrion-Lacritick A, Frangeul L, Couderc E, Gausson V, Blanc H, Bergman A, Baidaliuk A, Romoli O, Saleh MC, Lambrechts L, Multifaceted contributions of Dicer2 to arbovirus transmission by Aedes aegypti., Cell Rep 2023 Aug; 42(8): 112977.
  • 2023
    Yann Aquino, Aurélie Bisiaux, Zhi Li, Mary O'Neill, Javier Mendoza-Revilla, Sarah Hélène Merkling, Gaspard Kerner, Milena Hasan, Valentina Libri, Vincent Bondet, Nikaïa Smith, Camille de Cevins, Mickaël Ménager, Francesca Luca, Roger Pique-Regi, Giovanna Barba-Spaeth, Stefano Pietropaoli, Olivier Schwartz, Geert Leroux-Roels, Cheuk-Kwong Lee, Kathy Leung, Joseph Wu, Malik Peiris, Roberto Bruzzone, Laurent Abel, Jean-Laurent Casanova, Sophie Valkenburg, Darragh Duffy, Etienne Patin, Maxime Rotival, Lluis Quintana-Murci, Dissecting human population variation in single-cell responses to SARS-CoV-2, Nature, 2023, 53 (8), pp.e2250307. ⟨10.1038/s41586-023-06422-9⟩.
  • 2021
    Pelleau S, Woudenberg T, Rosado J, Donnadieu F, Garcia L, Obadia T, Gardais S, Elgharbawy Y, Velay A, Gonzalez M, Nizou JY, Khelil N, Zannis K, Cockram C, Merkling SH, Meola A, Kerneis S, Terrier B, de Seze J, Planas D, Schwartz O, Dejardin F, Petres S, von Platen C, Pellerin SF, Arowas L, de Facci LP, Duffy D, Cheallaigh CN, Dunne J, Conlon N, Townsend L, Duong V, Auerswald H, Pinaud L, Tondeur L, Backovic M, Hoen B, Fontanet A, Mueller I, Fafi-Kremer S, Bruel T, White M, Kinetics of the Severe Acute Respiratory Syndrome Coronavirus 2 Antibody Response and Serological Estimation of Time Since Infection., J Infect Dis 2021 Nov; 224(9): 1489-1499.
  • 2021
    Smith N, Goncalves P, Charbit B, Grzelak L, Beretta M, Planchais C, Bruel T, Rouilly V, Bondet V, Hadjadj J, Yatim N, Pere H, Merkling SH, Ghozlane A, Kernéis S, Rieux-Laucat F, Terrier B, Schwartz O, Mouquet H, Duffy D, Di Santo JP, , Distinct systemic and mucosal immune responses during acute SARS-CoV-2 infection., Nat Immunol 2021 Sep; 22(11):1428-1439.
  • 2021
    Rosado J, Pelleau S, Cockram C, Merkling SH, Nekkab N, Demeret C, Meola A, Kerneis S, Terrier B, Fafi-Kremer S, de Seze J, Bruel T, Dejardin F, Petres S, Longley R, Fontanet A, Backovic M, Mueller I, White MT, , Multiplex assays for the identification of serological signatures of SARS-CoV-2 infection: an antibody-based diagnostic and machine learning study., Lancet Microbe 2021 Feb; 2(2): e60-e69.
  • 2020
    Aubry F, Dabo S, Manet C, Filipović I, Rose NH, Miot EF, Martynow D, Baidaliuk A, Merkling SH, Dickson LB, Crist AB, Anyango VO, Romero-Vivas CM, Vega-Rúa A, Dusfour I, Jiolle D, Paupy C, Mayanja MN, Lutwama JJ, Kohl A, Duong V, Ponlawat A, Sylla M, Akorli J, Otoo S, Lutomiah J, Sang R, Mutebi JP, Cao-Lormeau VM, Jarman RG, Diagne CT, Faye O, Faye O, Sall AA, McBride CS, Montagutelli X, Rašić G, Lambrechts L, , Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations., Science 2020 11; 370(6519): 991-996.
  • 2020
    Suzuki Y, Baidaliuk A, Miesen P, Frangeul L, Crist AB, Merkling SH, Fontaine A, Lequime S, Moltini-Conclois I, Blanc H, van Rij RP, Lambrechts L, Saleh MC, , Non-retroviral Endogenous Viral Element Limits Cognate Virus Replication in Aedes aegypti Ovaries., Curr Biol 2020 09; 30(18): 3495-3506.e6.
  • 2020
    Hadjadj J, Yatim N, Barnabei L, Corneau A, Boussier J, Smith N, Péré H, Charbit B, Bondet V, Chenevier-Gobeaux C, Breillat P, Carlier N, Gauzit R, Morbieu C, Pène F, Marin N, Roche N, Szwebel TA, Merkling SH, Treluyer JM, Veyer D, Mouthon L, Blanc C, Tharaux PL, Rozenberg F, Fischer A, Duffy D, Rieux-Laucat F, Kernéis S, Terrier B, , Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients., Science 2020 08; 369(6504): 718-724.
  • 2020
    Dickson LB, Merkling SH, Gautier M, Ghozlane A, Jiolle D, Paupy C, Ayala D, Moltini-Conclois I, Fontaine A, Lambrechts L, , Exome-wide association study reveals largely distinct gene sets underlying specific resistance to dengue virus types 1 and 3 in Aedes aegypti., PLoS Genet 2020 05; 16(5): e1008794.
  • 2020
    Halbach R, Miesen P, Joosten J, Taşköprü E, Rondeel I, Pennings B, Vogels CBF, Merkling SH, Koenraadt CJ, Lambrechts L, van Rij RP, , A satellite repeat-derived piRNA controls embryonic development of Aedes., Nature 2020 04; 580(7802): 274-277.
  • 2020
    Merkling SH, Raquin V, Dabo S, Henrion-Lacritick A, Blanc H, Moltini-Conclois I, Frangeul L, Varet H, Saleh MC, Lambrechts L, , Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut., iScience 2020 Feb; 23(2): 100870.
  • 2020
    Merkling SH, Lambrechts L, , Taking Insect Immunity to the Single-Cell Level., Trends Immunol 2020 03; 41(3): 190-199.
  • 2019
    Baidaliuk A, Miot EF, Lequime S, Moltini-Conclois I, Delaigue F, Dabo S, Dickson LB, Aubry F, Merkling SH, Cao-Lormeau VM, Lambrechts L, , Cell-Fusing Agent Virus Reduces Arbovirus Dissemination in Aedes aegypti Mosquitoes In Vivo., J Virol 2019 09; 93(18): .
  • 2019
    Riahi H, Brekelmans C, Foriel S, Merkling SH, Lyons TA, Itskov PM, Kleefstra T, Ribeiro C, van Rij RP, Kramer JM, Schenck A, , The histone methyltransferase G9a regulates tolerance to oxidative stress-induced energy consumption., PLoS Biol 2019 03; 17(3): e2006146.
  • 2019
    Merkling SH, Riahi H, Overheul GJ, Schenck A, van Rij RP, , Peroxisome-associated Sgroppino links fat metabolism with survival after RNA virus infection in Drosophila., Sci Rep 2019 02; 9(1): 2065.
  • 2018
    Poirier EZ, Goic B, Tomé-Poderti L, Frangeul L, Boussier J, Gausson V, Blanc H, Vallet T, Loyd H, Levi LI, Lanciano S, Baron C, Merkling SH, Lambrechts L, Mirouze M, Carpenter S, Vignuzzi M, Saleh MC, , Dicer-2-Dependent Generation of Viral DNA from Defective Genomes of RNA Viruses Modulates Antiviral Immunity in Insects., Cell Host Microbe 2018 Mar; 23(3): 353-365.e8.
  • 2017
    Raquin V, Merkling SH, Gausson V, Moltini-Conclois I, Frangeul L, Varet H, Dillies MA, Saleh MC, Lambrechts L, , Individual co-variation between viral RNA load and gene expression reveals novel host factors during early dengue virus infection of the Aedes aegypti midgut., PLoS Negl Trop Dis 2017 12; 11(12): e0006152.
  • 2015
    Merkling SH, Overheul GJ, van Mierlo JT, Arends D, Gilissen C, van Rij RP, , The heat shock response restricts virus infection in Drosophila., Sci Rep 2015 Aug; 5(): 12758.
  • 2015
    Merkling SH, van Rij RP, , Analysis of resistance and tolerance to virus infection in Drosophila., Nat Protoc 2015 Jul; 10(7): 1084-97.
  • 2015
    Merkling SH, Bronkhorst AW, Kramer JM, Overheul GJ, Schenck A, Van Rij RP, , The epigenetic regulator G9a mediates tolerance to RNA virus infection in Drosophila., PLoS Pathog 2015 Apr; 11(4): e1004692.
  • 2013
    Merkling SH, van Rij RP, , Beyond RNAi: antiviral defense strategies in Drosophila and mosquito., J Insect Physiol 2013 Feb; 59(2): 159-70.
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