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Guides
  • 2021
    Pinto G, Saenz-de-Santa-Maria I, Chastagner P, Perthame E, Delmas C, Toulas C, Moyal-Jonathan-Cohen E, Brou C, Zurzolo C, , Patient-derived glioblastoma stem cells transfer mitochondria through tunneling nanotubes in tumor organoids., Biochem J 2021 01; 478(1): 21-39.
  • 2020
    Chastagner P, Loria F, Vargas JY, Tois J, I Diamond M, Okafo G, Brou C, Zurzolo C, , Fate and propagation of endogenously formed Tau aggregates in neuronal cells., EMBO Mol Med 2020 Nov; (): e12025.
  • 2020
    Pinto G, Brou C, Zurzolo C, , Tunneling Nanotubes: The Fuel of Tumor Progression?, Trends Cancer 2020 Oct; 6(10): 874-888.
  • 2014
    Puca L, Brou C, Α-arrestins – new players in Notch and GPCR signaling pathways in mammals, J. Cell. Sci. 2014 Apr;127(Pt 7):1359-67.
  • 2014
    Chastagner P, Brou C, Tracking trafficking of Notch and its ligands in mammalian cells, Methods Mol. Biol. 2014;1187:87-100.
  • 2013
    Puca L, Chastagner P, Meas-Yedid V, Israël A, Brou C, Α-arrestin 1 (ARRDC1) and β-arrestins cooperate to mediate Notch degradation in mammals, J. Cell. Sci. 2013 Oct;126(Pt 19):4457-68.
  • 2012
    Moretti J, Chastagner P, Liang CC, Cohn MA, Israël A, Brou C, The ubiquitin-specific protease 12 (USP12) is a negative regulator of notch signaling acting on notch receptor trafficking toward degradation, J. Biol. Chem. 2012 Aug;287(35):29429-41.
  • 2010
    Moretti J, Chastagner P, Gastaldello S, Heuss SF, Dirac AM, Bernards R, Masucci MG, Israël A, Brou C, The translation initiation factor 3f (eIF3f) exhibits a deubiquitinase activity regulating Notch activation, PLoS Biol. 2010;8(11):e1000545.
  • 2008
    Brou C, Intracellular trafficking of Notch receptors and ligands, Exp. Cell Res. 2009 May;315(9):1549-55.
  • 2008
    Chastagner P, Israël A, Brou C, AIP4/Itch regulates Notch receptor degradation in the absence of ligand, PLoS ONE 2008;3(7):e2735.
  • 2006
    Chastagner P, Israël A, Brou C, Itch/AIP4 mediates Deltex degradation through the formation of K29-linked polyubiquitin chains, EMBO Rep. 2006 Nov;7(11):1147-53.
  • 2005
    Olry A, Chastagner P, Israël A, Brou C, Generation and characterization of mutant cell lines defective in gamma-secretase processing of Notch and amyloid precursor protein, J. Biol. Chem. 2005 Aug;280(31):28564-71.
  • 2004
    Six EM, Ndiaye D, Sauer G, Laâbi Y, Athman R, Cumano A, Brou C, Israël A, Logeat F, The notch ligand Delta1 recruits Dlg1 at cell-cell contacts and regulates cell migration, J. Biol. Chem. 2004 Dec;279(53):55818-26.
  • 2004
    Gupta-Rossi N, Six E, LeBail O, Logeat F, Chastagner P, Olry A, Israël A, Brou C, Monoubiquitination and endocytosis direct gamma-secretase cleavage of activated Notch receptor, J. Cell Biol. 2004 Jul;166(1):73-83.
  • 2003
    Six E, Ndiaye D, Laabi Y, Brou C, Gupta-Rossi N, Israel A, Logeat F, The Notch ligand Delta1 is sequentially cleaved by an ADAM protease and gamma-secretase, Proc. Natl. Acad. Sci. U.S.A. 2003 Jun;100(13):7638-43.
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