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  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
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© Research
Project

Pharmacological prevention and treatment of long-term cognitive and behavioral effects of neuroinflammation

Project leader: Franck Verdonk
Project leader: Fabrice Chretien
Member: Anne Danckaert
Member: Gabriela Ferreira de Medeiros
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
03
Nov 2014
Keywords
8 Keywords
Status
Ongoing
Members
4

About

Several recent results suggest an involvement of inflammation in depression and consecutive cognitive impairment. The antidepressant effects of pharmacological molecules may be related to their anti-inflammatory properties mediated  by a microglial action. The objective of this study is to investigate in an inflammatory animal model of depression the impact of the preventive or therapeutic injection of pharmacological molecules on microglial cell, depressive behavior and cognitive impairment.

Fundings