Lucie Peduto, head of the unit ‘Stroma, inflammation and tissue repair’, received the European Research Council (ERC) Proof of concept grant for her project ‘REACT – Reprogramming of Tumor Stroma to Enhance Cancer Immunotherapy’. She is among the 240 researchers in Europe (and 22 in France) to receive this prestigious grant in 2023.
Immunotherapy is a type of cancer treatment that helps your immune system’s natural ability to fight cancer. Some immunotherapies, such as immune checkpoints inhibitors, showed notable success in cancer treatment. However, the response is often partial and efficacy remains low in certain cancers, notably due to the development of resistance mechanisms within the tumor microenvironment. This project aims at investigating novel approaches targeting the tumor microenvironment to improve efficacy of immunotherapy in resistant cancers.