Search anything and hit enter
  • Teams
  • Members
  • Projects
  • Events
  • Calls
  • Jobs
  • publications
  • Software
  • Tools
  • Network
  • Equipment

A little guide for advanced search:

  • Tip 1. You can use quotes "" to search for an exact expression.
    Example: "cell division"
  • Tip 2. You can use + symbol to restrict results containing all words.
    Example: +cell +stem
  • Tip 3. You can use + and - symbols to force inclusion or exclusion of specific words.
    Example: +cell -stem
e.g. searching for members in projects tagged cancer
Search for
Count
IN
OUT
Content 1
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Content 2
  • member
  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Department Manager
  • Full Professor
  • Graduate Student
  • Honorary Professor
  • Lab assistant
  • Non-permanent Researcher
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
Search
Go back
Scroll to top
Share
© Institut Pasteur
Macrophages et lymphocytes de souris. Image colorisée.
Scientific Fields
Diseases
Organisms
Applications
Technique
Click to view graph
Connections

CV

EDUCATION

Sep 2014 Jun 2017     Wuhan Institute of Biological Products          Pathogen Biology              Master

Sep 2010 Jun 2014     South-central University for Nationalities     Bioengineering                   Bachelor

 

 

PAPERS

▪ Low Toxicity and High Immunogenicity of an Inactivated Vaccine Candidate against COVID-19 in different animal models. Emerging Microbes & Infections. DOI:10.1080/22221751.2020.1852059

▪ Animal models of dengue virus infection. Chin J Microbiol Immunol, 2017,37(9): 712-720. DOI: 10.3760/cma.j.issn.0254-5101.2017.09.012

▪ Genetic characteristics analysis of Echovirus 11 in Xiangyang, Hubei between 2016 and 2017. Chin J Microbiol Immunol. (Submitted)

▪ Establishment and validation of an assay of Vero cell residual DNA in an inactivated, whole virus SARS-CoV-2 vaccine using magnetic bead-based extraction combined with quantitative Real-Time PCR. Chin J Microbiol Immunol. (Submitted)

 

RESEARCH EXPERIENCE

Jan 2020 present  : SARS-CoV-2 inactivated vaccine                                                   Team member
▪ Immunogenicity and tolerance of a vaccine candidate in different animal models: mouse, rat, guinea pig, rabbit, rhesus monkey
▪ Safety evaluation of candidate vaccine in cynomolgus monkey
▪ Neutralization antibody test: serum of subjects from Phase Ⅰ/Ⅱ/Ⅲ Clinical trial
▪ Participation of standardization of an assay assigned by China National Institutes for Food and Drug Control: using pseudovirus to determine anti-SARS-CoV-2 neutralization antibody in animal and human samples
▪ Quality  control:  Testing  residual  host  cell  DNA  and  adventitious  agents  during purification process, and presence of Mycoplasma, monitoring the genetic stability of virus seeds by conventional and deep sequencing.

Jul 2017 present : Multivalent hand and foot disease inactivated vaccine             Team member
▪ Virus isolation and plaque purification
▪ Immunogenicity in different animal models: mouse, rat
▪ Safety evaluation of multivalent candidate vaccines in cynomolgus monkey
▪ Formulation study of a multivalent, inactivated vaccine candidate against hand, foot and mouth disease (HFMD)
▪ Collaborative calibration of national neutralizing antibody standard products of CVA6, CVA10
▪ Quality control: Stability of multivalent HFMD, inactivated vaccine including virus titration, the genetic stability of virus seed, detection of residual host cell DNA and adventitious agents during purification process and finished products

Sep 2014 Jun 2017 : Mouse model of Dengue virus                                                            Research project
▪ Establish a lethal infection model of 14-day-old ICR mouse to evaluate the candidate vaccine and drugs
▪ Involved in data processing, technique work on virus culture and purification, cell culture, viral titration, animal experiments, immunofluorescence, ELISA, Western Blot and other molecular biology related experiments.

 

ACITIVITIES

Oct 2020Nov 2020 : NGS information and data processing in Beijing Computing Center

Nov 2018 : 13th Annual meeting Chinese society for immunology in Shanghai

Aug 2015Sep 2015 :“Biotechnology and vaccine research and development” Graduate Summer School hosted by Chinese Academy of medical sciences & Peking Union Medical College.

 

HONOR & SCHOLARSHIP

Oct 2020 : Second Prize of 2020 “Creating Youth” Hubei Youth

Jun 2020 : Awards for anti-epidemic work in CNBG

Dec 2018 : Excellent team Awards in Wuhan Institute of Biological Products Co., Ltd

Apr 2014 :Third prize of Academic Scholarship