Sylvie joined the Zurzolo lab as a technician in 2014, and is currently working with Aysegul Dilsizoglu-Senol (Post-doc), studying the transfer of alpha-synuclein via tunneling nanotubes and the role of lysosomes in the propagation of alpha-synuclein. Sylvie is specialized in cell culture: cell lines, primary culture of neurons, primary astrocytes, and organotypic brain slices.
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2021α-Synuclein fibrils subvert lysosome structure and function for the propagation of protein misfolding between cells through tunneling nanotubes., PLoS Biol 2021 Jul; 19(7): e3001287.
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2019The Wnt/Ca2+ pathway is involved in interneuronal communication mediated by tunneling nanotubes., EMBO J 2019 12; 38(23): e101230.
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2018Rab11a-Rab8a cascade regulates the formation of tunneling nanotubes through vesicle recycling, J. Cell. Sci. 2018 Oct;131(19).
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2018Morphodynamics of the Actin-Rich Cytoskeleton in Entamoeba histolytica, Front Cell Infect Microbiol. 2018 May 29;8:179.
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2017α-Synuclein transfer between neurons and astrocytes indicates that astrocytes play a role in degradation rather than in spreading., Acta Neuropathologica, 2017, pp.1-20. ⟨10.1007/s00401-017-1746-2⟩.
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2016Differential identity of Filopodia and Tunneling Nanotubes revealed by the opposite functions of actin regulatory complexes, Sci Rep 2016 Dec;6:39632.
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2016PrPC Undergoes Basal to Apical Transcytosis in Polarized Epithelial MDCK Cells, PLoS ONE 2016;11(7):e0157991.
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2016Intracellular traffic of the lysine and glutamic acid rich protein KERP1 reveals features of endomembrane organization in Entamoeba histolytica, Cell. Microbiol. 2016 Aug;18(8):1134-52.
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2016Astrocyte-to-neuron intercellular prion transfer is mediated by cell-cell contact, Sci Rep 2016 Feb;6:20762.
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2014Data set for the proteomics analysis of the endomembrane system from the unicellular Entamoeba histolytica, Data Brief 2014 Dec;1:29-36.
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