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  • team
  • department
  • center
  • program_project
  • nrc
  • whocc
  • project
  • software
  • tool
  • patent
  • Administrative Staff
  • Assistant Professor
  • Associate Professor
  • Clinical Research Assistant
  • Clinical Research Nurse
  • Clinician Researcher
  • Department Manager
  • Dual-education Student
  • Full Professor
  • Honorary Professor
  • Lab assistant
  • Master Student
  • MD-PhD Student
  • Medical Staff
  • Non-permanent Researcher
  • Nursing Staff
  • Permanent Researcher
  • Pharmacist
  • PhD Student
  • Physician
  • Post-doc
  • Prize
  • Project Manager
  • Research Associate
  • Research Engineer
  • Retired scientist
  • Technician
  • Undergraduate Student
  • Veterinary
  • Visiting Scientist
  • Deputy Director of Center
  • Deputy Director of Department
  • Deputy Director of National Reference Center
  • Deputy Head of Facility
  • Director of Center
  • Director of Department
  • Director of Institute
  • Director of National Reference Center
  • Group Leader
  • Head of Facility
  • Head of Operations
  • Head of Structure
  • Honorary President of the Departement
  • Labex Coordinator
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Scientific Fields
Diseases
Organisms
Applications
Technique

About

Ours projects aim at dissecting in vivo host-parasite interactions in humanized mouse models optimized for human hematopoiesis, immune responses, and Plasmodium infection, specifically targeting both the blood stage and extravascular compartments.

Projects

Project
Completed
4 Members

Plasmodium vivax Invasion Pathways into Human Reticulocytes

Didier Ménard (PI)

Erythrocyte invasion is a complex process involving multiple interactions between Plasmodium merozoites and host erythrocytes. Unlike P. falciparum, which can use multiple erythrocyte receptors for invasion and has merozoite proteins with overlapping and redundant […]
Project
Ongoing
2 Members

Establishment of new humanized mice and chronic human diseases.

Sylvie Garcia (PI)

Over the last decades, many efforts have been made to establish human/mouse hematopoietic chimeras as models for “human” diseases, that would allow to dissect pathological mechanisms and to design new therapies and vaccines. Although […]
Project
Completed
3 Members

Regulation of innate CD8 memory T cells during Salmonella typhimurium infection.

Sylvie Garcia (PI)

The role of innate response of CD8 memory T cell during infections is now well established. However, while the mechanisms that govern its induction and mode of actions in particular IFNg secretion are more […]

Publications

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