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© Research
Publication : Immunology letters

Humanized mice: current states and perspectives

Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Immunology letters - 09 Apr 2012

Garcia S, Freitas AA

Link to Pubmed [PMID] – 22507217

Immunol. Lett. 2012 Aug;146(1-2):1-7

The development of chimeric mice bearing the components of a human immune system to serve as animal models for “human” diseases has been the goal of many years of research. In this review we will discuss the latest advances in this field, their remaining shortcomings and challenges to the generation of new models of mouse/human chimeras.

http://www.ncbi.nlm.nih.gov/pubmed/22507217