Imaginons la recherche
“Imaginons la recherche” is a project for supporting structural change in research organisations to promote Responsible Research and Innovation (RRI) as defined by the european commission : Public engagement (outreach & citizen science) Gender […]
Interferon induction, inflammation and stress in HCV infection and stress-related pathologies
While potentially able to activate an immune response, the Hepatitis C virus establishes in a chronic infection in the majority of patients with progressive inflammation and degradation of the liver over time. Intensive research […]
Interaction of HCV with the IFN and stress pathways
Cells respond to invasion by bacterial or viral pathogens with the production of IFNs and pro-inflammatory cytokines, as a first line of their innate immune response. This is due to their ability to detect […]
Chronic infections with Hepatitis C (HCV) and Hepatitis B (HBV) viruses
Chronic infections with Hepatitis C (HCV) and Hepatitis B (HBV) viruses (which infect 170 and 350 million persons in the world, respectively) lead to development of cirrhosis and are responsible for 80% of hepatocellular […]
2021Recent African strains of Zika virus display higher transmissibility and fetal pathogenicity than Asian strains., Nat Commun 2021 02; 12(1): 916.
2020Enhanced Zika virus susceptibility of globally invasive Aedes aegypti populations., Science 2020 11; 370(6519): 991-996.
2020Tudor-SN Promotes Early Replication of Dengue Virus in the Aedes aegypti Midgut., iScience 2020 Feb; 23(2): 100870.
2017Inhibition of the inflammatory response to stress by targeting interaction between PKR and its cellular activator PACT, Sci Rep. 2017 Nov 23;7(1):16129.