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© Research
Member: PhD Student - Alumni

Marta Mastrogiovanni

Alumni
Scientific Fields
Diseases
Organisms
Applications
Technique

Projects

Project
Completed
7 Members

Projet de Recherche Clinique : Impact des mutations du gène APC (Adenomatous polyposis coli) dans les réponses immunes anti-tumorales

Andres Alcover (PI)

La polypose adénomateuse familiale est une maladie caractérisée par l’apparition dans l’intestin de nombreux polypes susceptibles d‘évoluer en cancer en l’absence de prise en charge. Il s’agit d’une maladie génétique rare, le plus souvent […]
Project
Completed
16 Members

CoSImmGEn-F : constitution d’une cohorte de sujets atteints de polypose adénomateuse familiale et porteurs d’une mutation du gène APC afin d’étudier le rôle de la génétique du système immunitaire et de l’environnement dans la maladie

Hélène Laude (PI)

Rationnel La polypose adénomateuse familiale se manifeste par l’apparition dans l’intestin de nombreuses excroissances dénommées polypes adénomateux et susceptibles d‘évoluer en cancers en l’absence de prise en charge. Il s’agit d’une maladie génétique, le […]
Project
Ongoing
11 Members

Cytoskeleton, immunological synapse and T cell activation: role of Ezrin and Adenomatous polyposis coli

Andres Alcover (PI)

Antigen recognition by the T cell receptor triggers extensive rearrangements of both the actin and microtubule cytoskeleton. Cytoskeleton changes condition in turn morphological changes and molecular reorganization at the immunological synapse (Figure). We have […]

CV

WORK EXPERIENCES

CURRENT- PhD student studying how cytoskeletal structures can shape and drive immune functions, orchestrating productive anti-tumor immune responses. I am particularly interested in the role of Apc (Adenomatous Polyposis Coli) protein in the control of T cell polarity and migration

2015 – 2017, Department of Biology and Biotechnology Charles Darwin, Università La Sapienza, Rome – Internship on cellular and molecular immunology, laboratory of Professor Loretta Tuosto

2017, Department of biochemical sciences Alessandro Rossi Fanelli, Università La Sapienza, Rome  – Internship on biochemistry, laboratory of Doctor Maria Carmela Bonaccorsi

2015, IBDM Developmental Biology Institute of Marseille, Marseille – Internship on signalling networks for tumorigenesis, laboratory of Doctor Flavio Maina, under the supervision of Doctor María Arechederra-Calderon

EDUCATION

Master’s Degree in Biology and Cellular Technologies (July 2017, Università La Sapienza, Rome)

Bachelor’s Degree in Biological Sciences (November 2015, Università La Sapienza, Rome)

SCHOLARSHIPS

Prize for “Excellent student of the academic year 2016-2017” of the Faculty of Mathematics, Physics and Natural Sciences at Sapienza University of Rome

Merit-based scholarship for 2016-2017 best student of the Master course “Biology and Cellular Technologies” at Sapienza University of Rome

Erasmus Scholarship for a semester-internship (year 2014) at the Aix-Marseille University (AMU)

Publications

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