Role of cytoplasmic dynein during Japanese encephalitis virus infectious cycle
This project examines the impact of dynein inhibition on Japanese encephalitis virus (JEV) infectious cycle. Several Flaviviruses (JEV, West Nile virus, yellow fever virus, Zika virus) show alteration of their infectious cycle in the […]
Mutation in Japanese Encephalitis and West Nile virus M protein affects late stages of virus life cycle and pathogenesis.
Flavivirus pre-membrane (prM) protein is important in assembly of viral particles. Its ectodomain is well conserved among flaviviruses. Previous work has shown that expression of this domain can trigger apoptosis in mammalian cells and […]