I received my PhD from Sapienza-University of Rome (Italy) in 2014. I investigated the regulation of HLA-E molecule expression during the monocyte-to-macrophage differentiation process as well as their role in the crosstalk between mononuclear phagocytes and Natural Killer cells. I also participated in a project whose main objective was to study the expression and role of ADAR enzymes in human myeloid leukemia cells.
I then joined the Immunology of Fungal Infection unit at the Pasteur Institute as a Postdoctoral researcher in December 2015 where I’m studying the b–glucans immunobiology. My research interests focus, in particular, on deciphering the b–glucan-mediated modulation of mononuclear phagocyte functions and of innate immune responses. These natural compounds have recently gained significant attention in the biomedical field for their antibacterial, antifungal and anticancer activities. A better understanding of their immunomodulating properties is, therefore, essential to make them potential candidates as therapeutic agents.