After completing my undergraduate studies in Algiers, I joined the “Haematopoiesis and Immunity lab” led by Dr. Marc Haenlin and Dr. Lucas Waltzer at the “Centre de Biologie du Développement” in Toulouse. I investigated the impact of nutrition and the role of the Insulin/Target-Of-Rapamycin signalling pathway, as well as the role of a specialised microenvironment, called the haematopoietic niche, on blood system homeostasis. After my PhD, I once again moved north to join the “Apoptosis and Proliferation Control Laboratory” led by Dr Nic Tapon at the Francis Crick Institute in London. There, I investigated upstream signals regulating the Hippo tumour suppressor pathway. Then, I came back to France and I joined the “Brain plasticity in response to the environment lab” led by Dr. Pauline Spéder at the Institut Pasteur.
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Publications
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2021Brain inflammation triggers macrophage invasion across the blood-brain barrier in Drosophila during pupal stages., Sci Adv 2021 Oct; 7(44): eabh0050.
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2021Breaking down barriers: Tumors make a leaky brain., Dev Cell 2021 Oct; 56(19): 2683-2685.
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2020An original infection model identifies host lipoprotein import as a route for blood-brain barrier crossing., Nat Commun 2020 11; 11(1): 6106.