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Paola Minoprio (PI)
Concerted effort to address rational drug design against Chagas disease Through a multidisciplinary approach that combine medicinal chemistry, structural bioinformatics, molecular docking and immunobiology of the infectious process, we identified two new inhibitors of […]
2023The crystal structure of a simian Foamy Virus receptor binding domain provides clues about entry into host cells., Nat Commun 2023 Mar; 14(1): 1262.
2023Structure, function, and evolution of the Orthobunyavirus membrane fusion glycoprotein., Cell Rep 2023 Feb; 42(3): 112142.
2023Structure and dynamic association of an assembly platform subcomplex of the bacterial type II secretion system., Structure. 2023 Feb 2;31(2):152-165.e7. doi: 10.1016/j.str.2022.12.003. Epub 2022 Dec 30. PMID: 36586404.
2023Trypanosoma brucei RRP44: a versatile enzyme for processing structured and non-structured RNA substrates, Nucleic Acids Res . 2023 Jan 11;51(1):380-395. doi: 10.1093/nar/gkac1199..
2022FtsEX-independent control of RipA-mediated cell separation in Corynebacteriales., Proc Natl Acad Sci U S A 2022 Dec; 119(50): e2214599119.
2022Dynamics and structural changes of calmodulin upon interaction with the antagonist calmidazolium., BMC Biol 2022 08; 20(1): 176.
2022Structural basis for the allosteric inhibition of UMP kinase from Gram-positive bacteria, a promising antibacterial target., FEBS J 2022 Feb; (): .
2022Structural basis of synergistic neutralization of Crimean-Congo hemorrhagic fever virus by human antibodies, Mishra et al., Science 375, 104–109 (2022).
2022Interactions of Severe Acute Respiratory Syndrome Coronavirus 2 Protein E With Cell Junctions and Polarity PSD-95/Dlg/ZO-1-Containing Proteins., Front Microbiol 2022 ; 13(): 829094.
2021Integrative Study of the Structural and Dynamical Properties of a KirBac3.1 Mutant: Functional Implication of a Highly Conserved Tryptophan in the Transmembrane Domain., Int J Mol Sci 2021 Dec; 23(1): .
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