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© Cédric Delevoye
Cellules infectÈes par Chlamydia trachomatis. Les bactÈries se dÈveloppent dans une vacuole (rouge), ‡ proximitÈ du noyau de la cellule-hÙte (bleu). Ce compartiment interagit de faÁon Ètroite avec ceux de la cellule hÙte. Marquage vert= localisation d'une protÈine de l'hÙte, Vamp8, exprimÈe par transfection. Les Chlamydia sont, selon les souches, responsables de maladies sexuellement transmises, de cÈcitÈs, d'infections pulmonaires et pourraient Ítre impliquÈes dans l'athÈrosclÈrose.
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Dec 2024
2024-12-31 8:00:00 2024-12-31 18:00:00 Europe/Paris Institut Pasteur Paris – Post-doctoral position Cell biology/ Epigenetics Project: The project is part of a transdisciplinary effort funded by ANR to find new therapeutic approaches to fight infection using epigenetic drugs. Our consortium combines expertise in the biology and […] "25-28 rue du Dr. Roux, 75015, Paris" Agathe Subtil agathe.subtil@pasteur.fr

Cell biology/ Epigenetics

Project: The project is part of a transdisciplinary effort funded by ANR to find new therapeutic approaches to fight infection using epigenetic drugs. Our consortium combines expertise in the biology and epigenetics of infection (5 teams), in proteomics (1 team) and in drug-design and medicinal chemistry of epigenetics (2 teams). Using Chlamydia trachomatis as a model organism, the post-doctoral fellow in the Subtil team will identify epigenetic-targeted molecules that jeopardize Chlamydia’s ability to dampen the inflammatory response of the host to infection, and unravel the underlying mechanisms.

Candidate: The post-doc, a highly motivated research fellow, will have a strong background in cell biology, and in epigenetics. Experience in microbiology is not required.

Diploma required: PhD.

Location: The Institut Pasteur in Paris offers an international, dynamic and stimulating scientific campus. The Institut Pasteur is located in the center of Paris and houses outstanding facilities for sequencing, microscopy, biochemistry and bioinformatics that provide access to state-of-the-art technology. The successful candidate will thus be integrated in a highly collaborative and supportive environment and will have the opportunity to develop multiple skills.

Funding

The position is fully funded for 2 years with possibilities for extension.

Salary will be commensurate to experience following the Institut Pasteur pay scale.

More information:

Host laboratory: Cell biology of microbial infection

PI: Agathe SUBTIL

Please visit our web site : https://research.pasteur.fr/en/team/cellular-biology-of-microbial-infection/

Selection process: starts September 2023 and will be continued until staffing.

To apply, please submit (i) a motivation letter, (ii) a full CV including a publication list, and (iii) the contact address of three referees.

Send applications to: Agathe Subtil  asubtil@pasteur.fr   Tel : +33 1 40 61 30 49