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© Research
Event

Mycology department seminar – Duncan Wilson “The fungal zincophore as a key determinant in zinc scavenging and immunopathology”

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
25
Nov 2021
Time
12:00:00
Institut Pasteur, Rue du Docteur Roux, Paris, France
Address
Building: Fernbach Room: Salle Jean-Paul Aubert
Location
2021-11-25 12:00:00 2021-11-25 13:00:00 Europe/Paris Mycology department seminar – Duncan Wilson “The fungal zincophore as a key determinant in zinc scavenging and immunopathology” Séminaire du Département Mycologie  Duncan Wilson Medical Research Council Centre for Medical Mycology, University of Exeter, UK  “The fungal zincophore as a key determinant in zinc scavenging and immunopathology”  Jeudi 25 novembre 2021, 12h00 […] Institut Pasteur, Rue du Docteur Roux, Paris, France Iuliana Ene iuliana.ene@pasteur.fr

About

Séminaire du Département Mycologie

 Duncan Wilson
Medical Research Council Centre for Medical Mycology, University of Exeter, UK

 The fungal zincophore as a key determinant in zinc scavenging and immunopathology

 Jeudi 25 novembre 2021, 12h00

Salle Jean-Paul Aubert
et Teams meeting : Cliquez ici pour participer à la réunion

Contact : Iuliana Ene (iuliana.ene@pasteur.fr)

Abstract :
Our immune systems effectively prevent the vast majority of microbes from causing disease. One of the fundamental mechanisms underpinning this defence is called “nutritional immunity”.
This is a system in which the human body withholds access to certain essential trace minerals that microbes require for growth. Pathogenic microbes therefore must have evolved strategies to circumvent nutritional immunity in order to grow within their host and cause disease.
In this seminar I will talk about the fungal specific zinc scavenging system – the Pra1 zincophore. The evolution of the genes encoding this system will be discussed and I will present new data showing how the zincophore drives immunopathology during candidiasis.

Location

Building: Fernbach
Room: Salle Jean-Paul Aubert
Address: Institut Pasteur, Rue du Docteur Roux, Paris, France