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© Research
Event

Developmental and Stem Cell Biology Department seminar by Antoine H.F.M. Peters, FMI Basel, Switzerland

Scientific Fields
Diseases
Organisms
Applications
Technique
Date
20
Apr 2018
Time
11:00:00
25 Rue du Dr Roux, Paris, France
Address
Building: Monod Room: Amphi Monod
Location
2018-04-20 11:00:00 2018-04-20 00:00:00 Europe/Paris Developmental and Stem Cell Biology Department seminar by Antoine H.F.M. Peters, FMI Basel, Switzerland “PRC2: versatile transcriptional regulators during pre-implantation development of the mouse” In mammals, fusion of two highly differentiated gametes gives rise to a totipotent zygote capable of developing into a whole organism. The switch in […] 25 Rue du Dr Roux, Paris, France Pablo Navarro Gil pablo.navarro-gil@pasteur.fr

About

“PRC2: versatile transcriptional regulators during pre-implantation development of the mouse”

In mammals, fusion of two highly differentiated gametes gives rise to a totipotent zygote capable of developing into a whole organism. The switch in cell fate coincides with translation and degradation of maternally provided transcripts, initiation of global transcription called zygotic genome activation (ZGA), and “epigenetic reprogramming” of germline chromatin states into an embryonic state, occurring in part in a parent-of-origin specific manner.

My laboratory is interested in the role of Polycomb Group (PcG) proteins and associated chromatin states in gene regulation in the germ line, in pre-implantation embryos and in intergenerational epigenetic inheritance. I will discuss our ongoing research in addressing these questions.

Location

Building: Monod
Room: Amphi Monod
Address: 25 Rue du Dr Roux, Paris, France