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© Institut Pasteur
Structure de macromolécules : dimère d'aquométhémoglobine de cheval. Dérivé toxique oxydé de l'hémoglobine, représentant 1 à 2% du total.
Equipment

Differential Scanning Fluorimetry NanoDSF Prometheus

Scientific Fields
Diseases
Organisms
Applications
Technique

Nanotemper • Prometheus

NanoDSF Prometheus  measures thermal denaturation of proteins by following the modification of the fluorescent environment of their aminoacids Tyrosines and Tryptophanes.

The machine can perform fast and sensitive simultaneus analyse of 48 distinct samples using only 10 µL of preparation at very low concentration.

The Prometheus measures also the back scattering of the sample, giving insight to the aggregation processus possibly coming with denaturation process.