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© Research
Publication : FEBS letters

The complete mitochondrial genome sequence of the pathogenic yeast Candida (Torulopsis) glabrata

Team: Biomics
Member: Agnès Thierry
Member: Romain Koszul
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in FEBS letters - 16 Jan 2003

Koszul R, Malpertuy A, Frangeul L, Bouchier C, Wincker P, Thierry A, Duthoy S, Ferris S, Hennequin C, Dujon B

Link to Pubmed [PMID] – 12527359

FEBS Lett. 2003 Jan;534(1-3):39-48

We report here the complete sequence of the mitochondrial (mt) genome of the pathogenic yeast Candida glabrata. This 20 kb mt genome is the smallest among sequenced hemiascomycetous yeasts. Despite its compaction, the mt genome contains the genes encoding the apocytochrome b (COB), three subunits of ATP synthetase (ATP6, 8 and 9), three subunits of cytochrome oxidase (COX1, 2 and 3), the ribosomal protein VAR1, 23 tRNAs, small and large ribosomal RNAs and the RNA subunit of RNase P. Three group I introns each with an intronic open reading frame are present in the COX1 gene. This sequence is available under accession number AJ511533.