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© Research
Publication : Eukaryotic cell

Stress by heat shock induces massive down regulation of genes and allows differential allelic expression of the Gal/GalNAc lectin in Entamoeba histolytica

Team: Biomics
Member: Christian Weber
Member: Odile Sismeiro
Member: Jean-Yves Coppee
Member: Nancy Guillen
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Eukaryotic cell - 01 May 2006

Weber C, Guigon G, Bouchier C, Frangeul L, Moreira S, Sismeiro O, Gouyette C, Mirelman D, Coppee JY, Guillén N

Link to Pubmed [PMID] – 16682464

Eukaryotic Cell 2006 May;5(5):871-5

Gene expression analysis by microarray assay revealed that when exposed to stress, Entamoeba histolytica exhibits a specific heat shock response, together with a dramatic overall reduction in gene transcription as well as differential allelic expression of key genes participating in virulence, such as the galactose/N-acetylgalactosamine (Gal/GalNAc) lectin.