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© Research
Publication : Malaria journal

FlexiChip package: an universal microarray with a dedicated analysis software for high-thoughput SNPs detection linked to anti-malarial drug resistance

Team: Biomics
Team: Bioinformatics and Biostatistics HUB
Member: Jean-Yves Coppee
Member: Christiane Bouchier
Member: Marie-Agnès Dillies
Member: Odile Sismeiro
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Malaria journal - 15 Oct 2009

Steenkeste N, Dillies MA, Khim N, Sismeiro O, Chy S, Lim P, Crameri A, Bouchier C, Mercereau-Puijalon O, Beck HP, Imwong M, Dondorp AM, Socheat D, Rogier C, Coppée JY, Ariey F

Link to Pubmed [PMID] – 19828052

Malar. J. 2009;8:229

A number of molecular tools have been developed to monitor the emergence and spread of anti-malarial drug resistance to Plasmodium falciparum. One of the major obstacles to the wider implementation of these tools is the absence of practical methods enabling high throughput analysis. Here a new Zip-code array is described, called FlexiChip, linked to a dedicated software program, which largely overcomes this problem.