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© Institut Pasteur/Antoinette Ryter
Salmonella spp. Bactéries à Gram négatif, aérobies ou anaérobies facultatifs à transmission orofécale. Les salmonelles majeures (sérotype typhi et sérotype paratyphi) sont responsables des fièvres typhoïde et paratyphoïde chez l'homme uniquement ; les salmonelles mineures (sérotype typhimurium et sérotype enteritidis) sont impliquées dans 30 à 60 % des gastroentérites et toxiinfections d'origine alimentaire. Image colorisée.
Publication : Journal of clinical microbiology

Global phylogeny of Shigella sonnei strains from limited single nucleotide polymorphisms (SNPs) and development of a rapid and cost-effective SNP-typing scheme for strain identification by high-resolution melting analysis

Team: Enteric Bacterial Pathogens
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Journal of clinical microbiology - 31 Oct 2012

Sangal V, Holt KE, Yuan J, Brown DJ, Filliol-Toutain I, Weill FX, Kim DW, da Silveira WD, Pickard D, Thomson NR, Parkhill J, Yu J

Link to Pubmed [PMID] – 23115259

J. Clin. Microbiol. 2013 Jan;51(1):303-5

The current Shigella sonnei pandemic involves geographically associated, multidrug-resistant clones. This study has demonstrated that S. sonnei phylogeny can be accurately defined with limited single nucleotide polymorphisms (SNPs). By typing 6 informative SNPs using a high-resolution melting (HRM) assay, major S. sonnei lineages/sublineages can be identified as defined by whole-genome variation.