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© Research
Project

Comparative genomics clostridium strains involved in necrotizing enterocolitis of the preterm newborn

Project leader: Julio Aires
Member: Marc Monot
Scientific Fields
Diseases
Organisms
Applications
Technique
Starting Date
01
Mar 2014
Keywords
5 Keywords
Ending Date
01
Sep 2017
Status
Ongoing
Members
2

About

Necrotizing enterocolitis (NEC) is the most common and serious gastrointestinal disorder among preterm neonates. We aimed to assess specific gut microbes associated with NEC. In 2002, an outbreak of NEC occurred in six neonates within a 2-month period in a Canadian neonatal intensive care unit. Recently, C. neonatale and Clostridium butyricum, Clostridium species involved in NEC, were significantly overrepresented among colonic mucosal samples from premature piglets with NEC. The aim of this project is to compare multiple strains of Clostridia that are responsible or not for NEC.

ClosNEC

Fundings