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© Ahmed Haouz
Cristaux d'une protéine de Mycobacterium tuberculosis produits dans le cadre du Grand Programme Horizontal sur la Tuberculose à l'Institut Pasteur. La caractérisation structurale de protéines mycobactériennes aide à une meilleure compréhension de la physiologie et de la pathogénicité des mycobactéries et fournit un point de départ pour la conception de nouveaux agents antibactériens.
Member: Head of Structure

Ahmed Haouz

• Crystallography

Platform: Crystallography
Scientific Fields
Diseases
Organisms
Applications
Technique

Projects

Project
Ongoing
7 Members

DNA-binding mechanism and evolution of replication protein A

Ludovic Sauguet (PI)

Replication Protein A (RPA) is a heterotrimeric single stranded DNA-binding protein with essential roles in DNA replication, recombination and repair. Little is known about the structure of RPA in Archaea, the third domain of […]
Project
Ongoing
10 Members

Chagas

Paola Minoprio (PI)

Concerted effort to address rational drug design against Chagas disease Through a multidisciplinary approach that combine medicinal chemistry, structural bioinformatics, molecular docking and immunobiology of the infectious process, we identified two new inhibitors of […]

Publications

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