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© Michaela Muller-Trutwin
HIV
Publication : Medecine sciences : M/S

[Evolution and virulence of primate lentiviruses].

Team: HIV, Inflammation and Persistence
Member: Michaela Muller-Trutwin
Scientific Fields
Diseases
Organisms
Applications
Technique

Published in Medecine sciences : M/S - 01 Apr 2004

Courgnaud V, Müller-Trutwin M, Sonigo P,

Link to Pubmed [PMID] – 15124118

Med Sci (Paris) 2004 Apr; 20(4): 448-52

While the AIDS epidemic caused by human immunodeficiency viruses (HIV) has resulted in the death of over 20 million people worldwide, simian immunodeficiency virus (SIV) infection, found in numerous African primate species, does not induce disease symptoms. The factors accounting for this difference between humans and natural host of SIV remain poorly understood. The entangled nature of the host/virus relationship could be the answer, rather than independent virus or host factors. Such a relationship is as a consequence of host/virus adaptation which has evolved over long periods in naturally infected primate species.