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Nursing Staff
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Deputy Director of Department
Deputy Director of National Reference Center
Deputy Head of Facility
Director of Center
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Group Leader
Head of Facility
Head of Operations
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Honorary President of the Departement
Labex Coordinator

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Malaria rapid diagnostic test as point-of-care test: study protocol for evaluating the VIKIA Malaria Ag Pf/Pan

Genome Sequence of Corynebacterium ulcerans Strain FRC11

Publication : AIDS (London, England)

Low SAMHD1 expression following T-cell activation and proliferation renders CD4+ T cells susceptible to HIV-1

Team: Virus and Immunity

Member: Olivier Schwartz

Scientific Fields

Diseases

Organisms

Applications

Technique

Published in AIDS (London, England) - 13 Mar 2015

Ruffin N, Brezar V, Ayinde D, Lefebvre C, Schulze Zur Wiesch J, van Lunzen J, Bockhorn M, Schwartz O, Hocini H, Lelievre JD, Banchereau J, Levy Y, Seddiki N

Link to Pubmed [PMID] – 25715102

AIDS 2015 Mar;29(5):519-30

HIV-1 replication depends on the state of cell activation and division. It is established that SAMHD1 restricts HIV-1 infection of resting CD4 T cells. The modulation of SAMHD1 expression during T-cell activation and proliferation, however, remains unclear, as well as a role for SAMHD1 during HIV-1 pathogenesis.

Published on: 13 Mar 2015